Primate Monocytes - CD14, CD16 - Ziegler-Heitbrock

Heterogeneity of human blood monocytes: the CD14⁺CD16⁺ subpopulation

Abstract

Previously, human blood monocyte subpopulations were defined by approaches that required their isolation, such as differential sedimentation or adherence. Therefore, enumeration of subpopulations and their analysis in disease remained difficult. Here Löms Ziegler-Heitbrock suggests that expression of CD14 and CD16 can be used to define at least two subsets of monocytes with distinct functional properties.