Human Monocytes - CD14, CD16 - Ziegler-Heitbrock

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Our work with Mono Mac 6

Authors
Title
Journal
Year
Abstract
PubMed
Hofer TP, Frankenberger M, Mages J, Lang R, Meyer P, Hoffmann R, Colige A, Ziegler-Heitbrock L.:
Tissue-specific induction of ADAMTS2 in monocytes and macrophages by glucocorticoids
J Mol Med. Mar;86(3):323-32
2008
Abstract PubMed
Frankenberger M, Schwaeble W, Ziegler-Heitbrock L:
Expression of M-Ficolin in human monocytes and macrophages
Mol Immunol., 45(5):1424-1430
2008
Abstract PubMed
Benkhart EM, Siedlar M, Wedel A, Werner T, Ziegler-Heitbrock HW:
Role of stat3 in lipopolysaccharide-induced IL-10 gene expression
J Immunol 165: 1612-1617
2000
Abstract PubMed
Page S, Fischer C, Baumgartner B, Haas M, Kreusel U, Loidl G, Hayn M, Ziegler-Heitbrock HW, Neumeier D, Brand K:
4-Hydroxynonenal Prevents NF-kappaB Activation and Tumor Necrosis Factor Expression by Inhibiting IkappaB Phosphorylation and Subsequent Proteolysis
J Biol Chem 274(17): 11611-11618
1999
Abstract PubMed
Kastenbauer S, Ziegler-Heitbrock H W:
NF-kappaB1 (p50) is upregulated in lipopolysaccharide tolerance and can block tumor necrosis factor gene expression
Infect Immun 67: 1553-91
1999
Abstract PubMed
Kaijzel EL, van Krugten MV, Brinkman BM, Huizinga TW, van der Straaten T, Hazes JM, Ziegler-Heitbrock HW, Nedospasov SA, Breedveld FC, Verweij CL:
Functional analysis of a human tumor necrosis factor alpha (TNF-alpha) promoter polymorphism related to joint damage in rheumatoid arthritis
Mol Med 4: 724-33
1998
Abstract PubMed
Frankenberger, M., Ziegler-Heitbrock, H.W.L.:
LPS tolerance in monocytes/macrophages: Three 3' cytosins are required in the DNA binding motif for detection of upregulated NF-kappa B p50 homodimers
Immunobiology, 198: 81-90
1997
Abstract PubMed
Frankenberger, M., Hofmann, B., Emmerich, B., Nerl, C., Schwendener, R.A., Ziegler-Heitbrock, H.W.L.:
Liposomal 1,25 (OH)2 vitamin D3 compounds block proliferation and induce differentiation in myelomonocytic leukaemia cells
Brit. J. Haematol., 98: 186-194
1997
Abstract PubMed
Wedel, A., Sulski, G., Ziegler-Heitbrock, H.W.L.:
CCAAT/Enhancer binding protein is involved in the expression of the tumour necrosis factor gene in human monocytes
Cytokine, 8: 335-341
1996
Abstract PubMed
Frankenberger, M., Pechumer, H., Ziegler-Heitbrock, H.W.L.:
Interleukin-10 is upregulatedin LPS tolerance
J. Inflammation, 45: 56-63
1995
Abstract PubMed
Frankenberger, M., Pforte, A., Sternsdorf, T., Passlick, B., Bäuerle, P.A., Ziegler-Heitbrock, H.W.L.:
Constitutive nuclear NF-KB in cells of the monocyte lineage
Biochem. J., 304: 87-94
1994
Abstract PubMed
Durieux, J.-J., Vita, N., Popescu, O., Guette, F., Calzada-Wack, J., Munker, R., Schmidt, R.E., Lupker, J., Ferrara, P., Ziegler-Heitbrock, H.W.L., Labeta, M.O.:
The two soluble forms of the lipopolysaccharide receptor, CD14: characterization and release by normal human monocytes
Eur. J. Immunol., 24: 2006-2012
1994
Abstract PubMed
Scheithe, R., Hrboticky, N., Ziegler-Heitbrock, H.W.L., and Weber, P.C.:
Receptor-specific uptake and degradation of acetylated oxidized and native LDL in the human monocytic Mono Mac 6sr cell line
Biochem. Biophys. Res. Communications, 202:334-339
1994
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Wedel, A., Schraut, W., Ströbel, M., Wendelgaß, P., Sternsdorf, T., Bäuerle, P.A., Haas, J.G., and Riethmüller, G.:
Tolerance to lipopolysaccharide involves mobilization of nuclear factor KB with predominance of p50 homodimers
J. Biol. Chem., 269: 17001-17004
1994
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Schraut, W., Wendelgaß, P., Ströbel, M., Sternsdorf, T., Weber, C., Aepfelbacher, M., Ehlers, M., Schütt, C., Haas, J.G.:
Distinct patterns of differentiation induced in the monocytic cell line Mono Mac 6
J. Leukocyte Biol., 55: 73-80
1994
Abstract PubMed
Schwäble, W., Hümer, H.P., Möst, J., Dierich, M.P., Ströbel, M., Claus, C., Reid, K.B.M., Ziegler-Heitbrock, H.W.L.:
Expression of properdin in human monocytes
Eur. J. Biochem., 219:759-764
1994
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Sternsdorf, T., Liese, J., Belohradsky, B., Weber, C., Wedel, A., Schreck, R., Bäuerle, P., Ströbel, M.:
Pyrrolidine dithiocarbamate inhibits NF-KB mobilization and TNF production in human monocytes
J. Immunol., 151:6986-6993
1993
Abstract PubMed
Weber, C., Aepfelbacher, M., Haag, H., Ziegler-Heitbrock, H.W.L., and Weber, P.C.:
Tumor necrosis factor induces enhanced responses to platelet activating factor and differentiation in human monocytic Mono Mac 6 cells
Eur. J. Immunol., 23:852-859
1993
Abstract PubMed
Thieblemont, N., Haeffner-Cavaillon, N., Ledur, A., L'age-Stehr, J., Ziegler-Heitbrock, H.W.L., Kazatchkine, M.D.:
CR1 (CD35) and CD3 (CD11b/CD18) mediate infection of human monocytes and monocytic cell lines with complement-opsonized HIV independently of CD4
Clin. Exp. Immunol., 92:106-113
1993
Abstract PubMed
Haas, J.G., Ströbel, M., Leutz, A., Wendelgaß, P., Müller, C., Sterneck, E., Riethmüller, G., Ziegler-Heitbrock, H.W.L.:
Constitutive monocyte-restricted activity of NF-M, a nuclear factor that binds to a C/EBP motif
J. Immunol., 149:237-243
1992
Abstract PubMed
Äpfelbacher, M., Ziegler-Heitbrock, H.W.L., Lux, I., Weber, P.C.:
Bacterial lipopolysaccharide up-regulates platelet-activating factor-stimulated Ca2+ mobilization and eicosanoid release in human Mono Mac 6 cells
J. Immunol., 148: 2186-2193
1992
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Käfferlein, E., Haas, J.G., Meyer, N., Ströbel, M., Weber, C., Flieger, D.:
Gangliosides suppress TNF production in human monocytes
J. Immunol., 148: 1753-1758
1992
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Blumenstein, M., Käfferlein, E., Kieper, D., Petersmann, I., Endres, S., Flegel, W., Northoff, H., Haas, J.G.:
In vitro desensitization to lipopolysaccharides suppresses TNF, IL-1 and IL-6 gene expression in a similar fashion
Immunology, 75: 264-268
1992
Abstract PubMed
L'age-Stehr, J.K., Niedrig, M., Sim-Brandenburg, J.W., Urban-Schriefer, M., Haas, J., Rieber, E.P., Gelderblom, H., Riethmüller, G., and Ziegler-Heitbrock, H.W.L.:
Infection of the human monocyte cell line Mono Mac 6 with HIV-1 and -2 results in long term production of virus variants with increased virulence for CD4+ T cells
J. Virol., 64: 3982-3987
1990
Abstract PubMed
Haas, J.G., Bäuerle, P.A., Riethmüller, G., Ziegler-Heitbrock, H.W.L.:
Molecular mechanism in down regulation of TNF expression
Proc. Natl. Acad. Sciences, 87: 9563-9567
1990
Abstract PubMed
Haas, J.G., Meyer, N., Ziegler-Heitbrock, H.W.L.:
Inhibition of lipopolysaccharide-induced in-vitro desensitization by interferon y
Eur. J. Immunol., 20:1181-1184
1990
Abstract PubMed
Haas, J.G., Thiel, C., Blömer, K., Weiss, E.H., Riethmüller, G., Ziegler-Heitbrock, H.W.L:
Downregulation of tumor necrosis factor expression in the human Mono-Mac-6 cell line by lipopolysaccharide
J. Leukocyte Biol., 46:11-14
1989
Abstract PubMed
Ziegler-Heitbrock, H.W.L., Thiel, E., Fütterer, A., Herzog, V., Wirtz, A., Riethmüller, G.:
Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes
Int. J. Cancer, 41:456-461
1988
Abstract PubMed

Work by others using Mono Mac 6

Authors
Title
Journal
Year
Abstract
PubMed
Palma L, Rossetti F, Dominici S, Buondelmonte C, Rocchi MB, Rizzardi GP, Vallanti G, Magnani M.:
Determination of Interference During In Vitro Pyrogen Detection: Development and Characterization of a Cell-Based Assay.
Assay Drug Dev Technol. 2017 Feb/Mar;15(2):64-76
2017
Abstract PubMed
Muramatsu D, Okabe M, Takaoka A, Kida H, Iwai A.:
Aureobasidium pullulans produced β-glucan is effective to enhance Kurosengoku soybean extract induced Thrombospondin-1 expression.
Sci Rep. 2017 Jun 6;7(1):283
2017
Abstract PubMed
Rohr M, Oleinikov K, Jung M, Sandjo LP, Opatz T, Erkel G.:
Anti-inflammatory tetraquinane diterpenoids from a Crinipellis species.
Bioorg Med Chem. 2017 Jan 15;25(2):514-522
2017
Abstract PubMed
Valenzuela NM, Thomas KA, Mulder A, Parry GC, Panicker S, Reed EF.:
Complement-Mediated Enhancement of Monocyte Adhesion to Endothelial Cells by HLA Antibodies, and Blockade by a Specific Inhibitor of the Classical Complement Cascade, TNT003.
Transplantation. 2017 Jul;101(7):1559-1572
2017
Abstract PubMed
Lawrence H, Deehan DJ, Holland JP, Anjum SA, Mawdesley AE, Kirby JA, Tyson-Capper AJ.:
Cobalt ions recruit inflammatory cells in vitro through human Toll-like receptor 4.
Biochem Biophys Rep. 2016 Jul 12;7:374-378
2016
Abstract PubMed
Anjum SA, Lawrence H, Holland JP, Kirby JA, Deehan DJ, Tyson-Capper AJ.:
Effect of cobalt-mediated Toll-like receptor 4 activation on inflammatory responses in endothelial cells.
Oncotarget. 2016 Nov 22;7(47):76471-76478.
2016
Abstract PubMed
Carter D, Fox CB, Day TA, Guderian JA, Liang H, Rolf T, Vergara J, Sagawa ZK, Ireton G, Orr MT, Desbien A, Duthie MS, Coler RN, Reed SG.:
A structure-function approach to optimizing TLR4 ligands for human vaccines.
Clin Transl Immunology. 2016 Nov 2;5(11):e108
2016
Abstract PubMed
Gregory MA, D Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J.:
ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678
2016
Abstract PubMed
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA.:
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810
2016
Abstract PubMed
Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC.:
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.
Blood. 2016 Jul 21;128(3):410-4
2016
Abstract PubMed
Gonnissen D, Qu Y, Langer K, Öztürk C, Zhao Y, Chen C, Seebohm G, Düfer M, Fuchs H, Galla HJ, Riehemann K.:
Comparison of cellular effects of starch-coated SPIONs and poly(lactic-co-glycolic acid) matrix nanoparticles on human monocytes.
Int J Nanomedicine. 2016 Oct 14;11:5221-5236.
2016
Abstract PubMed
Ábrahám Á, Baranyai Z, Gyulai G, Pári E, Horváti K, Bősze S, Kiss É.:
Comparative analysis of new peptide conjugates of antitubercular drug candidates-Model membrane and in vitro studies.
Colloids Surf B Biointerfaces. 2016 Nov 1;147:106-15
2016
Abstract PubMed
Zhang L, Stuber F, Lippuner C, Schiff M, Stamer UM.:
Phorbol-12-myristate-13-acetate induces nociceptin in human Mono Mac 6 cells via multiple transduction signalling pathways.
Br J Anaesth. 2016 Aug;117(2):250-7
2016
Abstract PubMed
Zariri A, Beskers J, van de Waterbeemd B, Hamstra HJ, Bindels TH, van Riet E, van Putten JP, van der Ley P.:
Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response.
Infect Immun. 2016 Sep 19;84(10):3024-33
2016
Abstract PubMed
Witola WH, Matthews K, McHugh M.:
In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus.
Int J Parasitol Drugs Drug Resist. 2016 Jan 18;6(1):44-53
2016
Abstract PubMed
Mohebbi S, Erfurth F, Hennersdorf P, Brakhage AA, Saluz HP.:
Hyperspectral Imaging Using Intracellular Spies: Quantitative Real-Time Measurement of Intracellular Parameters In Vivo during Interaction of the Pathogenic Fungus Aspergillus fumigatus with Human Monocytes.
PLoS One. 2016 Oct 11;11(10):e0163505
2016
Abstract PubMed
Ebner P, Rinker J, Nguyen MT, Popella P, Nega M, Luqman A, Schittek B, Di Marco M, Stevanovic S, Götz F.:
Excreted Cytoplasmic Proteins Contribute to Pathogenicity in Staphylococcus aureus.
Infect Immun. 2016 May 24;84(6):1672-81
2016
Abstract PubMed
Krejbich-Trotot P, Belarbi E, Ralambondrainy M, El-Kalamouni C, Viranaicken W, Roques P, Desprès P, Gadea G.:
The growth of arthralgic Ross River virus is restricted in human monocytic cells.
Virus Res. 2016 Sep 13;225:64-68
2016
Abstract PubMed
Lukic A, Ji J, Idborg H, Samuelsson B, Palmberg L, Gabrielsson S, Rådmark O.:
Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.
J Lipid Res. 2016 Sep;57(9):1659-69
2016
Abstract PubMed
Riemann A, Wußling H, Loppnow H, Fu H, Reime S, Thews O.:
Acidosis differently modulates the inflammatory program in monocytes and macrophages.
Biochim Biophys Acta. 2016 Jan;1862(1):72-81
2016
Abstract PubMed
Saul MJ, Stein S, Grez M, Jakobsson PJ, Steinhilber D, Suess B.:
UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance.
Sci Rep. 2016 Aug 30;6:31995
2016
Abstract PubMed
Vordenbäumen S, Saenger T, Braukmann A, Tahan T, Bleck E, Jose J, Schneider M.:
Human casein alpha s1 induces proinflammatory cytokine expression in monocytic cells by TLR4 signaling.
Mol Nutr Food Res. 2016 May;60(5):1079-89
2016
Abstract PubMed
Xiong Y, Murphy M, Manavalan TT, Pattabiraman G, Qiu F, Chang HH, Ho IC, Medvedev AE.:
Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.
J Innate Immun. 2016;8(2):171-84.
2016
Abstract PubMed
Hoonakker ME, Verhagen LM, Pupo E, de Haan A, Metz B, Hendriksen CF, Han WG, Sloots A.:
Vaccine-Mediated Activation of Human TLR4 Is Affected by Modulation of Culture Conditions during Whole-Cell Pertussis Vaccine Preparation.
PLoS One. 2016 Aug 22;11(8):e0161428
2016
Abstract PubMed
Poussin C, Laurent A, Peitsch MC, Hoeng J, De Leon H.:
Systems toxicology-based assessment of the candidate modified risk tobacco product THS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells.
Toxicology.;339:73-86
2016
Abstract PubMed
Chen CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N, Eng R, Doench JG, Xu H, Chu SH, Qi J, Wang X, Delaney C, Bernt KM, Root DE, Hahn WC, Bradner JE, Armstrong SA.:
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Nat Med. 2015 Apr;21(4):335-43
2015
Abstract PubMed
Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE.:
Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.
J Leukoc Biol. 2015 Dec;98(6):963-74
2015
Abstract PubMed
Charron CS, Dawson HD, Albaugh GP, Solverson PM, Vinyard BT, Solano-Aguilar GI, Molokin A, Novotny JA.:
A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans.
J Nutr. 145:2448-55
2015
Abstract PubMed
Lehmann C, Homann J, Ball AK, Blöcher R, Kleinschmidt TK, Basavarajappa D, Angioni C, Ferreirós N, Häfner AK, Rådmark O, Proschak E, Haeggström JZ, Geisslinger G, Parnham MJ, Steinhilber D, Kahnt AS.:
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
FASEB J.;29:5029-43.
2015
Abstract PubMed
Huber R, Panterodt T, Welz B, Christmann M, Friesenhagen J, Westphal A, Pietsch D, Brand K.:
C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation.
PLoS One;10:e0144338
2015
Abstract PubMed
Poussin C, Laurent A, Peitsch MC, Hoeng J, De Leon H.:
Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte-Endothelial Cell Adhesion.
Toxicol Sci. 147:370-85
2015
Abstract PubMed
Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M.:
Isoxanthohumol--Biologically active hop flavonoid.
Fitoterapia.;103:71-82.
2015
Abstract PubMed
Kleinschmidt TK, Haraldsson M, Basavarajappa D, Lundeberg E, Thulasingam M, Ekoff M, Fauland A, Lehmann C, Kahnt AS, Lindbom L, Haeggström JZ.:
Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
J Pharmacol Exp Ther. ;355:108-16
2015
Abstract PubMed
Kawata K, Iwai A, Muramatsu D, Aoki S, Uchiyama H, Okabe M, Hayakawa S, Takaoka A, Miyazaki T.:
Stimulation of macrophages with the β-glucan produced by aureobasidium pullulans promotes the secretion of tumor necrosis factor-related apoptosis inducing ligand (TRAIL).
PLoS One.;10:e0124809.
2015
Abstract PubMed
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G:
2. G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
Inflamm Bowel Dis.;21:1269-81
2015
Abstract PubMed
Baranyai Z, Krátký M, Vinšová J, Szabó N, Senoner Z, Horváti K, Stolaříková J, Dávid S, Bősze S.:
Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates.
Eur J Med Chem.;101:692-704
2015
Abstract PubMed
Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE.:
Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.
J Biol Chem.;290:19218-32
2015
Abstract PubMed
Nguyen MT, Kraft B, Yu W, Demicrioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Götz F.:
The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.
PLoS Pathog.;11:e1004984
2015
Abstract PubMed
Valenzuela NM, Trinh KR, Mulder A, Morrison SL, Reed EF.:
Monocyte recruitment by HLA IgG-activated endothelium: the relationship between IgG subclass and FcγRIIa polymorphisms.
Am J Transplant. ;15:1502-18
2015
Abstract PubMed
Hoonakker ME, Verhagen LM, Hendriksen CF, van Els CA, Vandebriel RJ, Sloots A, Han WG.:
In vitro innate immune cell based models to assess whole cell Bordetella pertussis vaccine quality: a proof of principle.
Biologicals.;43:100-9
2015
Abstract PubMed
Knape T, Flesch D, Kuchler L, Sha LK, Giegerich AK, Labocha S, Ferreirós N, Schmid T, Wurglics M, Schubert-Zsilavecz M, Proschak E, Brüne B, Parnham MJ, von Knethen A.:
Identification and characterisation of a prototype for a new class of competitive PPARγ antagonists.
Eur J Pharmacol.;755:16-26.
2015
Abstract PubMed
Haile LA, Puig M, Kelley-Baker L, Verthelyi D.:
Detection of innate immune response modulating impurities in therapeutic proteins.
PLoS One.;10:e0125078
2015
Abstract PubMed
Busch S, Auth E, Scholl F, Huenecke S, Koehl U, Suess B, Steinhilber D.:
5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5p.
J Immunol;194:1646-53
2015
Abstract PubMed
Brummelman J, Veerman RE, Hamstra HJ, Deuss AJ, Schuijt TJ, Sloots A, Kuipers B, van Els CA, van der Ley P, Mooi FR, Han WG, Pinelli E.:
Bordetella pertussis Naturally Occurring Isolates with Altered Lipooligosaccharide Structure Fail To Fully Mature Human Dendritic Cells.
Infect Immun.;83(1):227-38
2015
Abstract PubMed
Kim HS, Lim GY, Hwang J, Ryoo ZY, Huh TL, Lee S.:
Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia.
Int J Mol Med.;34:1675-80
2014
Abstract PubMed
É. Kiss, G. Gyulai, Cs. B. Pénzes, M. Idei, K. Horváti, B. Bacsa, Sz. Bősze:
Tuneable surface modification of PLGA nanoparticles carrying new antitubercular drug candidate
Colloids and Surfaces A: Physicochemical and Engineering Aspects 458: 178
2014
Abstract PubMed
Horváti K, Bacsa B, Kiss E, Gyulai G, Fodor K, Balka G, Rusvai M, Szabó E, Hudecz F, Bősze S.:
Nanoparticle encapsulated lipopeptide conjugate of antitubercular drug isoniazid: in vitro intracellular activity and in vivo efficacy in a Guinea pig model of tuberculosis.
Bioconjug Chem.;25:2260-8
2014
Abstract PubMed
Kim HS, Lim GY, Hwang J, Ryoo ZY, Huh TL, Lee S.:
Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia.
nt J Mol Med.;34:1675-80
2014
Abstract PubMed
Quang Trong Le, Sahar Lotfi-Emran, Hae-Ki Min, Lawrence B. Schwartz:
A Simple, Sensitive and Safe Method to Determine the Human α/β-Tryptase Genotype
PLoS One.; 9: e114944.
2014
Abstract PubMed
Lowe HI, Toyang NJ, Watson CT, Ayeah KN, Bryant J.:
Antileukemic activity of Tillandsia recurvata and some of its cycloartanes.
Anticancer Res.;34:3505-9.
2014
Abstract PubMed
Pierzchalski P1, Jastrzebska M, Link-Lenczowski P, Leja-Szpak A, Bonior J, Jaworek J, Okon K, Wojcik P.:
The dynamics of heat shock system activation in Monomac-6 cells upon Helicobacter pylori infection.
J Physiol Pharmacol.;65(6):791-800.
2014
Abstract PubMed
Ahmad K, Katryniok C, Scholz B, Merkens J, Löscher D, Marschalek R, Steinhilber D.:
Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL.
Oncogenesis.;3:e127
2014
Abstract PubMed
Wen B, Combes V, Bonhoure A, Weksler BB, Couraud PO, Grau GE.:
Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.
PLoS One.;9:e91597
2014
Abstract PubMed
Bollmann F, Art J, Henke J, Schrick K, Besche V, Bros M, Li H, Siuda D, Handler N, Bauer F, Erker T, Behnke F, Mönch B, Härdle L, Hoffmann M, Chen CY, Förstermann U, Dirsch VM, Werz O, Kleinert H, Pautz A.:
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.
Nucleic Acids Res.;42:12555-69
2014
Abstract PubMed
Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O.:
Melleolides induce rapid cell death in human primary monocytes and cancer cells.
Bioorg Med Chem. ;22:3856-61
2014
Abstract PubMed
Vijayan S, Asare Y, Grommes J, Soehnlein O, Lutgens E, Shagdarsuren G, Togtokh A, Jacobs MJ, Fischer JW, Bernhagen J, Weber C, Schober A, Shagdarsuren E.:
High expression of C5L2 correlates with high proinflammatory cytokine expression in advanced human atherosclerotic plaques.
Am J Pathol.;184:2123-33
2014
Abstract PubMed
Lawrence H, Deehan D, Holland J, Kirby J, Tyson-Capper A.:
The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip.
Bone Joint J. ;96-B :1172-7
2014
Abstract PubMed
Schäffler H, Demircioglu DD, Kühner D, Menz S, Bender A, Autenrieth IB, Bodammer P, Lamprecht G, Götz F, Frick JS.:
Receptor 2 Costimulation with Lipoproteins in Dendritic Cells.
Infect Immun.;82(11):4681-8.
2014
Abstract PubMed
Willi M, Belibasakis GN, Bostanci N.:
Expression and regulation of triggering receptor expressed on myeloid cells 1 in periodontal diseases.
Clin Exp Immunol.;178:190-200
2014
Abstract PubMed
Basavarajappa D, Wan M, Lukic A, Steinhilber D, Samuelsson B, Rådmark O.:
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Proc Natl Acad Sci U S A. ;111:11371-6
2014
Abstract PubMed
Friedrichs B, Neumann U, Schüller J, Peck MJ.:
Cigarette-smoke-induced priming of neutrophils from smokers and non-smokers for increased oxidative burst response is mediated by TNF-α.
Toxicol In Vitro.;28:1249-58
2014
Abstract PubMed
Pergola C, Gerstmeier J, Mönch B, Çalışkan B, Luderer S, Weinigel C, Barz D, Maczewsky J, Pace S, Rossi A, Sautebin L, Banoglu E, Werz O.:
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
Br J Pharmacol.;171:3051-64.
2014
Abstract PubMed
Witola WH, Liu SR, Montpetit A, Welti R, Hypolite M, Roth M, Zhou Y, Mui E, Cesbron-Delauw MF, Fournie GJ, Cavailles P, Bisanz C, Boyer K, Withers S, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Muench SP, McLeod R.:
ALOX12 in Human Toxoplasmosis
Infect Immun.;82:2670-2679
2014
Abstract PubMed
Markoutsa S, Sürün D, Karas M, Hofmann B, Steinhilber D, Sorg BL.:
Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS.
FEBS J. ;281:1931-47.
2014
Abstract PubMed
de Leeuw DC, Denkers F, Olthof MC, Rutten AP, Pouwels W, Jan Schuurhuis G, Ossenkoppele GJ, Smit L:
Attenuation of microRNA-126 expression that drives CD34+38- stem/progenitor cells in acute myeloid leukemia leads to tumor eradication.
Cancer Res.;74:2094-105.
2014
Abstract PubMed
Poussin C, Gallitz I, Schlage WK, Steffen Y, Stolle K, Lebrun S, Hoeng J, Peitsch MC, Lietz M.:
Mechanism of an indirect effect of aqueous cigarette smoke extract on the adhesion of monocytic cells to endothelial cells in an in vitro assay revealed by transcriptomics analysis.
Toxicol In Vitro.;28:896-908
2014
Abstract PubMed
Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV:
Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions.
Antimicrob Agents Chemother. 181:174-80
2014
Abstract PubMed
Zughaier SM, Kandler JL, Shafer WM.:
Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
PLoS One;9:e87688
2014
Abstract PubMed
Rye MS, Scaman ES, Thornton RB, Vijayasekaran S, Coates HL, Francis RW, Pennell CE, Blackwell JM, Jamieson SE.:
Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3.
BMC Med Genet.;15:18
2014
Abstract PubMed
Lauer SA, Iyer S, Sanchez T, Forst CV, Bowden B, Carlson K, Sriranganathan N, Boyle SM:
Proteomic Analysis of Detergent Resistant Membrane Domains during Early Interaction of Macrophages with Rough and Smooth Brucella melitensis.
PLoS One ;9:e91706
2014
Abstract PubMed
de Groote ML, Kazemier HG, Huisman C, van der Gun BT, Faas MM, Rots MG.:
Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.
Int J Cancer.;134:280-90
2014
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Pupo E1, Hamstra HJ, Meiring H, van der Ley P.:
Lipopolysaccharide engineering in Neisseria meningitidis: Structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties.
J Biol Chem.
2014
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Li Z, Zhang Z, Li Y, Arnovitz S, Chen P, Huang H, Jiang X, Hong GM, Kunjamma RB, Ren H, He C, Wang CZ, Elkahloun AG, Valk PJ, Döhner K, Neilly MB, Bullinger L, Delwel R, Löwenberg B, Liu PP, Morgan R, Rowley JD, Yuan CS, Chen J.:
PBX3 is an important cofactor of HOXA9 in leukemogenesis.
Blood. 2013 Feb 21;121(8):1422-31
2013
Abstract PubMed
Mastelic B, Garçon N, Del Giudice G, Golding H, Gruber M, Neels P, Fritzell B.:
Predictive markers of safety and immunogenicity of adjuvanted vaccines.
Biologicals 41:458-68
2013
Abstract PubMed
Kühnemuth B, Mühlberg L, Schipper M, Griesmann H, Neesse A, Milosevic N, Wissniowski T, Buchholz M, Gress TM, Michl P:
CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling.
Oncogene, 1-11
2013
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Tuszynski GP, Rothman VL.:
Angiocidin induces differentiation of acute myeloid leukemia cells.
Exp Mol Pathol.;95:249-54
2013
Abstract PubMed
Lee JC1, Espéli M, Anderson CA, Linterman MA, Pocock JM, Williams NJ, Roberts R, Viatte S, Fu B, Peshu N, Hien TT, Phu NH, Wesley E, Edwards C, Ahmad T, Mansfield JC, Gearry R, Dunstan S, Williams TN, Barton A, Vinuesa CG; UK IBD Genetics Consortium, Par:
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway
Cell.;155:57-69
2013
Abstract PubMed
Paland N1, Aharoni S, Fuhrman B.:
Urokinase-type plasminogen activator (uPA) modulates monocyte-to-macrophage differentiation and prevents Ox-LDL-induced macrophage apoptosis
Atherosclerosis.;231:29-38.
2013
Abstract PubMed
Khare, Naveen K.:
Design, synthesis and activity of thio-linked arabinofuranosyl disaccharides against mycobacterial tuberculosis (MTB) and Mycobacterium avium complex (MAC).
ARKIVOC(ii) 290-315
2013
Abstract PubMed
Valenzuela NM1, Hong L, Shen XD, Gao F, Young SH, Rozengurt E, Kupiec-Weglinski JW, Fishbein MC, Reed EF:
Blockade of p-selectin is sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro and in vivo
Am J Transplant;13:299-311
2013
Abstract PubMed
Xu J1, Mojsoska B.:
The immunomodulation effect of Aronia extract lacks association with its antioxidant anthocyanins
J Med Food;16:334-42
2013
Abstract PubMed
Timm M, Saaby L, Moesby L, Hansen EW.:
Considerations regarding use of solvents in in vitro cell based assays.
Cytotechnology.;65:887-94
2013
Abstract PubMed
Valenzuela NM, Mulder A, Reed EF:
HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs
J Immunol. ;190(12):6635-50
2013
Abstract PubMed
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järas M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root D:
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
Cancer Cell. pii: S1535-6108(13)00197-9
2013
Abstract PubMed
Wöbke TK, von Knethen A, Steinhilber D, Sorg BL:
CD69 Is a TGF-β/1α,25-dihydroxyvitamin D3 Target Gene in Monocytes
PLoS One. ;8(5):e64635.
2013
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Raby AC, Holst B, Le Bouder E, Diaz C, Ferran E, Conraux L, Guillemot JC, Coles B, Kift-Morgan A, Colmont CS, Szakmany T, Ferrara P, Hall JE, Topley N, Labeta MO:
Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens
Sci Transl Med. ;5(185):185ra64
2013
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Ochs MJ, Ossipova E, Oliynyk G, Steinhilber D, Suess B, Jakobsson PJ:
Mass spectrometry based proteomics identifies UPF1 as a critical gene expression regulator in Mono Mac 6 cells
J Proteome Res.
2013
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Hinterleitner C, Huelsenbeck J, Henninger C, Wartlick F, Schorr A, Kaina B, Fritz G:
Rac1 signaling protects monocytic AML cells expressing the MLL-AF9 oncogene from caspase-mediated apoptotic death
Apoptosis.
2013
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Ehlers C, Schirmer S, Kehlenbach RH, Hauber J, Chemnitz J:
Post-transcriptional regulation of CD83 expression by AUF1 proteins
Nucleic Acids Res. ;41(1):206-19
2013
Abstract PubMed
Rye MS, Wiertsema SP, Scaman ES, Thornton R, Francis RW, Vijayasekaran S, Coates HL, Jamieson SE, Blackwell JM:
Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population
Infect Genet Evol. 16:411-8
2013
Abstract PubMed
Xu J, Mojsoska B:
The immunomodulation effect of aronia extract lacks association with its antioxidant anthocyanins
J Med Food. ;16(4):334-42
2013
Abstract PubMed
Khare NK, Duarte FJ, Reynolds RC, Maddry JA:
Design, synthesis and activity of thio-linked arabinofuranosyl disaccharides against mycobacterial tuberculosis AND (MTB) AND and Mycobacterium avium complex AND (MAC)
ARKIVOC (ii) 290-315
2013
Abstract PubMed
Manosroi J, Tangjai T, Werner RG, Götz F, Manosroi W, Manosroi A:
Potent and Prolonged Hypoglycemic Activity of an Oral Insulin - Tat Mixture in Diabetic Mice
Drug Res (Stuttg).
2013
Abstract PubMed
Schepetkin IA, Kouakou K, Yapi A, Kirpotina LN, Jutila MA, Quinn MT:
Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum
Int Immunopharmacol. ;15(3):628-37
2013
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Lajko E, Szabo I, Andody K, Pungor A, Mezö G, Köhidai L:
Investigation on chemotactic drug targeting (chemotaxis and adhesion) inducer effect of GnRH-III derivatives in Tetrahymena and human leukemia cell line
J Pept Sci. ;19(1):46-58
2013
Abstract PubMed
Thomas AW, Davies NA, Moir H, Watkeys L, Ruffino JS, Isa SA, Butcher LR, Hughes MG, Morris K, Webb R.:
Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism.
J Appl Physiol ;112:806-15.
2012
Abstract PubMed
Kunnen A, Dekker DC, van Pampus MG, Harmsen HJ, Aarnoudse JG, Abbas F, Faas MM.:
Cytokine production induced by non-encapsulated and encapsulated Porphyromonas gingivalis strains.
Arch Oral Biol. 57:1558-66
2012
Abstract PubMed
Kunisch R, Kamal E, Lewin A:
The role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction
BMC Microbiol. 3;12:165
2012
Abstract PubMed
Müller-Schmah C, Solari L, Weis R, Pfeifer D, Scheibenbogen C, Trepel M, May AM, Engelhardt R, Lübbert M:
Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia
Ann Hematol. ;91(1):27-32
2012
Abstract PubMed
Raval A, Sridhar KJ, Patel S, Turnbull BB, Greenberg PL, Mitchell BS:
Reduced rRNA expression and increased rDNA promoter methylation in CD34+ cells of patients with myelodysplastic syndromes
Blood. 6;120(24):4812-8
2012
Abstract PubMed
Rodenburg GD, Fransen F, Bogaert D, Schipper K, Groenwold RH, Hamstra HJ, Westerhuis BM, van de Beek D, van der Ley P, Sanders EA, van der Ende A:
Prevalence and clinical course in invasive infections with meningococcal endotoxin variants
PLoS One. ;7(11):e49295
2012
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Bunuales M, Garcia-Aragoncillo E, Casado R, Quetglas JI, Hervas-Stubbs S, Bortolanza S, Benavides-Vallve C, Ortiz-de-Solorzano C, Prieto J, Hernandez-Alcoceba R:
Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer
Hum Gene Ther. ;23(12):1258-68
2012
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Kaszuba-Zwoinska J, Chorobik P, Juszczak K, Zaraska W, Thor PJ:
Pulsed electromagnetic field affects intrinsic and endoplasmatic reticulum apoptosis induction pathways in MonoMac6 cell line culture
J Physiol Pharmacol. ;63(5):537-45
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Abstract PubMed
Schreiber D, Jung M, Sandjo LP, Liermann JC, Opatz T, Erkel G:
3'-Demethyldihydromaldoxin and dihydromaldoxin, two anti-inflammtory diaryl ethers from a Steganospora species
J Antibiot (Tokyo). ;65(9):473-7
2012
Abstract PubMed
Kunnen A, Dekker DC, van Pampus MG, Harmsen HJ, Aarnoudse JG, Abbas F, Faas MM:
Cytokine production induced by non-encapsulated and encapsulated Porphyromonas gingivalis strains
Arch Oral Biol. 57: 1558-1566
2012
Abstract PubMed
Schepetkin IA, Kirpotina LN, Khlebnikov AI, Hanks TS, Kochetkova I, Pascual DW, Jutila MA, Quinn MT:
Identification and Characterization of a Novel Class of c-Jun N-terminal Kinase Inhibitors
Mol Pharmacol. ;81(6):832-45
2012
Abstract PubMed
Bostanci N, Belibasakis GN:
Doxycycline inhibits TREM-1 induction by Porphyromonas gingivalis
FEMS Immunol Med Microbiol. 66: 37-44
2012
Abstract PubMed
Zaitseva M, Romantseva T, Blinova K, Beren J, Sirota L, Drane D, Golding H:
Use of human MonoMac6 cells for development of in vitro assay predictive of adjuvant safety in vivo
Vaccine. 30: 4859-65
2012
Abstract PubMed
Horvati K, Bacsa B, Szabo N, David S, Mezö G, Grolmusz V, Vertessy B, Hudecz F, Bösze S:
Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation
Bioconjug Chem. 23: 900-907
2012
Abstract PubMed
Hausmann M, Zeitler C, Weber A, Krebs M, Kellermeier S, Rosenstiel P, de Valliere C, Kosovac K, Fried M, Holler E, Rogler G.:
MIP-3α Expression in Macrophages Is NOD Dependent
Digestion. ;85(3):192-201
2012
Abstract PubMed
Ochs MJ, Sorg BL, Pufahl L, Grez M, Suess B, Steinhilber D.:
Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay
PLoS One. ;7(2):e31363
2012
Abstract PubMed
Carignan D, Desy O, de Campos-Lima PO.:
The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors
Toxicol Sci. ;125(1):144-56
2012
Abstract PubMed
Lok CA, Snijder KS, Nieuwland R, Van Der Post JA, de Vos P, Faas MM.:
Microparticles of pregnant women and preeclamptic patients activate endothelial cells in the presence of monocytes
Am J Reprod Immunol. ;67(3):206-15.
2012
Abstract PubMed
Spratt DA, Daglia M, Papetti A, Stauder M, O Donnell D, Ciric L, Tymon A, Repetto B, Signoretto C, Houri-Haddad Y, Feldman M, Steinberg D, Lawton S, Lingström P, Pratten J, Zaura E, Gazzani G, Pruzzo C, Wilson M.:
Evaluation of plant and fungal extracts for their potential antigingivitis and anticaries activity
J Biomed Biotechnol. ;2012:510198.
2012
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Leurs U, Lajko E, Mezo G, Orban E, Ohlschläger P, Marquardt A, Kohidai L, Manea M.:
GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate
Eur J Med Chem.;52:173-83
2012
Abstract PubMed
Lajko E, Polgar L, Lang O, Lengyel J, Köhidai L, Magyar K.:
Basic cell physiological activities (cell adhesion, chemotaxis and proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes
J Neural Transm. ;119(5):545-56
2012
Abstract PubMed
Okuzaki D, Kimura S, Yabuta N, Ohmine T, Nojima H:
LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood
BMC Clin Pathol. ;11:9
2011
Abstract PubMed
Bostanci N, Thurnheer T, Belibasakis GN.:
Involvement of the TREM-1/DAP12 pathway in the innate immune responses to Porphyromonas gingivalis.
Mol Immunol. 49(1-2):387-94
2011
Abstract PubMed
Pufahl L, Katryniok C, Schnur N, Sorg BL, Metzner J, Grez M, Steinhilber D.:
Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3
J Cell Mol Med.; 16(7):1461-73
2011
Abstract PubMed
Kong Q, Six DA, Liu Q, Roland KL, Raetz CR, Curtiss R 3rd:
Palmitoylation state impacts innate and acquired immunity in the Salmonella enterica serovar Typhimurium msbB mutant
Infect Immun.;79(12):5027-38
2011
Abstract PubMed
Serwe A, Rudolph K, Anke T, Erkel G:
Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol
Invest New Drugs.;30(3):898-915
2011
Abstract PubMed
Huyton T, Göttmann W, Bade-Döding C, Paine A, Blasczyk R:
The T/NK cell co-stimulatory molecule SECTM1 is an IFN "early response gene" that is negatively regulated by LPS in Human monocytic cells
Biochim Biophys Acta.; 1810(12):1294-301
2011
Abstract PubMed
Kong Q, Six DA, Roland KL, Liu Q, Gu L, Reynolds CM, Wang X, Raetz CR, Curtiss R 3rd:
Salmonella synthesizing 1-monophosphorylated lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity
J Immunol. 187(1):412-23
2011
Abstract PubMed
Jung M, Liermann JC, Opatz T, Erkel G:
Ganodermycin, a novel inhibitor of CXCL10 expression from Ganoderma applanatum
J Antibiot (Tokyo) ; 64(10):683-686
2011
Abstract PubMed
Hansen C, Hansen EW, Hansen HR, Gammelgaard B, Stürup S.:
Reduction of Sb(V) in a Human Macrophage Cell Line Measured by HPLC-ICP-MS.
Biol Trace Elem Res.;144(1-3):234-43
2011
Abstract PubMed
Howard KM, Abdel-Al M, Ditmyer M, Patel N:
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways
Inflamm Res.;60(8):735-44.
2011
Abstract PubMed
Sano C, Tatano Y, Shimizu T, Yamabe S, Sato K, Tomioka H:
Comparative in vitro and in vivo antimicrobial activities of sitafloxacin, gatifloxacin and moxifloxacin against Mycobacterium avium
Int J Antimicrob Agents. ;37(4):296-301
2011
Abstract PubMed
Sarabi A, Kramp BK, Drechsler M, Hackeng TM, Soehnlein O, Weber C, Koenen RR, Von Hundelshausen P.:
CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment
J Thromb Haemost. ;9(1):209-19
2011
Abstract PubMed
Witola WH, Mui E, Hargrave A, Liu S, Hypolite M, Montpetit A, Cavailles P, Bisanz C, Cesbron-Delauw MF, Fournie GJ, McLeod R:
NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate of Toxoplasma gondii-Infected Monocytic Cells
Infect Immun. 79(2):756-66
2011
Abstract PubMed
Mannonen L, Markkula E, Puolakkainen M:
Analysis of Chlamydia pneumoniae infection in mononuclear cells by reverse transcription-PCR targeted to chlamydial gene transcripts
Med Microbiol Immunol.; 200(3):143-54
2011
Abstract PubMed
Vordenbäumen S, Braukmann A, Petermann K, Scharf A, Bleck E, von Mikecz A, Jose J, Schneider M:
Casein α s1 is expressed by human monocytes and upregulates the production of GM-CSF via p38 MAPK
J Immunol. ;186(1):592-601
2011
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Jaimes Y, Seltsam A, Eiz-Vesper B, Blasczyk R, Figueiredo C:
Regulation of HLA class II expression prevents allogeneic T-cell responses
Tissue Antigens. 77:36-44.
2011
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Esser J, Gehrmann U, Salvado MD, Wetterholm A, Haeggström JZ, Samuelsson B, Gabrielsson S, Scheynius A, Radmark O.:
Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors
FASEB J. 25(4):1417-27
2011
Abstract PubMed
Benfante R, Antonini RA, De Pizzol M, Gotti C, Clementi F, Locati M, Fornasari D.:
Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.
J Neuroimmunol. 230: 74-84
2011
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Chakrabarty S, Snyder JT, Shen J, Azmi H, Hu PQ, Chen Q, Ragheb JA:
Human CD14hi monocytes and myeloid dendritic cells provide a cell contact-dependent costimulatory signal for early CD40 ligand expression
Blood.; 117(5):1585-94
2010
Abstract PubMed
Kraemer S, Lue H, Zernecke A, Kapurniotu A, Andreetto E, Frank R, Lennartz B, Weber C, Bernhagen J:
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism
FASEB J.; 25(3):894-906
2010
Abstract PubMed
Liu J, Pankhurst LJ, Deacon LJ, Abate W, Hayes ET, Drew GH, Longhurst PJ, Pollard S, Longhurst J, Tyrrel SF, Jackson SK:
Evaluation of inflammatory effects of airborne endotoxin emitted from composting sources
Environ Toxicol Chem.; 30(3):602-6
2010
Abstract PubMed
Faas MM, van Pampus MG, Anninga ZA, Salomons J, Westra IM, Donker RB, Aarnoudse JG, de Vos P:
Plasma from preeclamptic women activates endothelial cells via monocyte activation in vitro
J Reprod Immunol. ;87(1-2):28-38
2010
Abstract PubMed
Szabó R, Bánóczi Z, Mező G, Láng O, Kőhidai L, Hudecz F.:
Daunomycin-polypeptide conjugates with antitumor activity.
Biochim Biophys Acta. 1798(12):2209-2216
2010
Abstract PubMed
Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T.:
Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals.
FASEB J. 24(10):4089-102
2010
Abstract PubMed
Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P.:
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
FASEB J.;25(1):314-25
2010
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Lombard C, Farthing D, Sun J, Fariss MW, McKallip RJ.:
Reference moist smokeless tobacco-induced apoptosis in human monocytes/macrophages cell line MM6.
Int Immunopharmacol. 10(9):1029-40
2010
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Richardson VJ.:
Divergent and synergistic regulation of matrix metalloprotease production by cytokines in combination with C-C chemokines.
Int J Immunopathol Pharmacol. 23(3):715-26
2010
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Parihar A, Eubank TD, Doseff AI.:
Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death.
J Innate Immun. 2(3):204-15
2010
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Saaby L, Jäger AK, Moesby L, Hansen EW, Christensen SB.:
Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.).
Phytother Res.; 25(2):195-201
2010
Abstract PubMed
Szabo R, Banoczi Z, Mezö G, Lang O, Köhidai L, Hudecz F.:
Daunomycin-polypeptide conjugates with antitumor activity.
Biochim Biophys Acta.; 1798(12):2209-16
2010
Abstract PubMed
Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T.:
Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals.
FASEB J. ; 24(10):4089-102
2010
Abstract PubMed
Funk D, Sorg BL, Lindner SC, Schmeiser HH.:
(32)P-postlabeling analysis of DNA adducts formed by leukotriene A(4) (LTA(4)).
Environ Mol Mutagen. 51(4):338-43
2010
Abstract PubMed
Moir H, Hughes MG, Potter S, Sims C, Butcher LR, Davies NA, Verheggen K, Jones KP, Thomas AW, Webb R.:
Exercise-induced Immunosuppression: The Roles of Reactive Oxygen Species and 5'AMP-activated Protein Kinase (AMPK) Dephosphorylation within Immune Cells.
J Appl Physiol.; 108(5):1284-92
2010
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de Zoete MR, Keestra AM, Roszczenko P, van Putten JP.:
Activation of human and chicken toll-like receptors by Campylobacter spp.
Infect Immun. 78(3):1229-38
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Fransen F, Heckenberg SG, Hamstra HJ, Feller M, Boog CJ, van Putten JP, van de Beek D, van der Ende A, van der Ley P.:
Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy
PLoS Pathog. ;5(4):e1000396
2009
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Jung M, Triebel S, Anke T, Richling E, Erkel G.:
Influence of apple polyphenols on inflammatory gene expression.
Mol Nutr Food Res. 53(10):1263-80
2009
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Gawad A, Ptak-Belowska A, Brzozowski T, Pawlik WW.:
Monocytes and vascular endothelial cells apoptosis. Role of p-HSP27.
J Physiol Pharmacol. 60(4):55-61
2009
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Aravindan N, Shanmugasundaram K, Natarajan M.:
Hyperthermia induced NFkappaB mediated apoptosis in normal human monocytes.
Mol Cell Biochem. 327(1-2):29-37
2009
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Breus VV, Heyes CD, Tron K, Nienhaus GU.:
Zwitterionic biocompatible quantum dots for wide pH stability and weak nonspecific binding to cells.
ACS Nano. 3(9):2573-80
2009
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Merhi F, Auger J, Rendu F, Bauvois B.:
Allium compounds, dipropyl and dimethyl thiosulfinates as antiproliferative and differentiating agents of human acute myeloid leukemia cell lines.
Biologics. 2(4):885-95.
2009
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Humphries J, Gossage JA, Modarai B, Burnand KG, Sisson TH, Murdoch C, Smith A.:
Monocyte urokinase-type plasminogen activator up-regulation reduces thrombus size in a model of venous thrombosis.
J Vasc Surg. 50(5):1127-34.
2009
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Esser J, Rakonjac M, Hofmann B, Fischer L, Provost P, Schneider G, Steinhilber D, Samuelsson B, Rådmark OP.:
Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.
Biochem J. 425(1):265-74
2009
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Stoffers KL, Sorg BL, Seuter S, Rau O, Rådmark O, Steinhilber D.:
Calcitriol Upregulates Open Chromatin and Elongation Markers at Functional Vitamin D Response Elements in the Distal Part of the 5-Lipoxygenase Gene.
J Mol Biol. 395(4):884-96
2009
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Sung TL, Rice AP.:
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Saad AF, Virella G, Chassereau C, Boackle RJ, Lopes-Virella MF:
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Analysis of proto-oncogene and heat-shock protein gene expression in human derived cell-lines exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field
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Nuclear translocation and DNA-binding activity of NFKB (NF-kappaB) after exposure of human monocytes to pulsed ultra-wideband electromagnetic fields (1 kV/cm) fails to transactivate kappaB-dependent gene expression
Radiat Res., 165(6):645-654
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Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I:
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Sorg BL, Klan N, Seuter S, Dishart D, Radmark O, Habenicht A, Carlberg C, Werz O, Steinhilber D:
Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site
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Blood, 107(8):3221-3228
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Majetschak M, Ponelies N, Hirsch T:
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Gene, 366:169-179
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Schmidt R, Redecke V, Breitfeld Y, Wantia N, Miethke T, Massberg S, Fischel S, Neumann FJ, Schomig A, May AE:
EMMPRIN (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes. Implications for plaque rupture
Thromb Haemost., 95(1): 151-158
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LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO:
Modulation of Neonatal Microbial Recognition: TLR-Mediated Innate Immune Responses Are Specifically and Differentially Modulated by Human Milk
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Poeckel D, Tausch L, George S, Jauch J, Werz O:
3-O-acetyl-11-keto-boswellic acid decreases basal intracellular Ca2+ levels and inhibits agonist-induced Ca2+ mobilization and mitogen-activated protein kinase activation in human monocytic cells
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Schmidt R, Bueltmann A, Ungerer M, Joghetaei N, Bulbul O, Thieme S, Chavakis T, Toole BP, Gawaz M, Schomig A, May AE:
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Aleksandrov DA, Zagryagskaya AN, Pushkareva MA, Bachschmid M, Peters-Golden M, Werz O, Steinhilber D, Sud'ina GF:
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Simkó M, Hartwig C, Lantow M, Lupke M, Mattsson MO, Rahman Q, Rollwitz J:
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Dishart D, Schnur N, Klan N, Werz O, Steinhilber D, Samuelsson B, Radmark O:
GC-rich sequences in the 5-lipoxygenase gene promoter are required for expression in Mono Mac 6 cells, characterization of a novel Sp1 binding site
Biochim Biophys Acta (Molecular and Cell Biology of Lipids) 1738: 37-47
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Kocer SS, Walker SG, Zerler B, Golub LM, Simon SR:
Metalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cells
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The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression
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Himes SR, Cronau S, Mulford C, Hume DA:
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Identification of molecular targets of the oligomeric non-prenylated acylphloroglucinols from Myrtus communis and their implication as anti-inflammatory compounds
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Naldini A, Bernini C, Pucci A, Carraro F:
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Mause SF, von Hundelshausen P, Zernecke A, Koenen RR, Weber C:
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Turpaev K, Bouton C, Diet A, Glatigny A, Drapier JC:
Analysis of differentially expressed genes in nitric oxide-exposed human monocytic cells
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Short communication: hydroperoxides in circulating lipids from dairy cows: implications for bioactivity of endogenous-oxidized lipids
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Neumeister B, Faigle M, Spitznagel D, Mainka A, Ograbek A, Wieland H, Mannowetz N, Rammensee HG:
Legionella pneumophila down-regulates MHC class I expression of human monocytic host cells and thereby inhibits T cell activation
Cell Mol Life Sci., 62(5):578-588
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Stoll H, Dengjel J, Nerz C, Gotz F:
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Wieland H, Ullrich S, Lang F, Neumeister B:
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Gauss KA, Bunger PL, Larson TC, Young CJ, Nelson-Overton LK, Siemsen DW, Quinn MT:
Identification of a novel tumor necrosis factor alpha-responsive region in the NCF2 promoter
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Tonks A, Parton J, Tonks AJ, Morris RH, Finall A, Jones KP, Jackson SK:
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Ferrante JV, Ferrante A:
Cutting edge: Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line
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Ostermann G, Fraemohs L, Baltus T, Schober A, Lietz M, Zernecke A, Liehn EA, Weber C:
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Johnson BJ, Le TT, Dobbin CA, Banovic T, Howard CB, Flores Fde M, Vanags D, Naylor DJ, Hill GR, Suhrbier A:
Heat Shock Protein 10 Inhibits Lipopolysaccharide-induced Inflammatory Mediator Production
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Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N:
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Kempf VA, Schairer A, Neumann D, Grassl GA, Lauber K, Lebiedziejewski M, Schaller M, Kyme P, Wesselborg S, Autenrieth IB:
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Baltus T, von Hundelshausen P, Mause SF, Buhre W, Rossaint R, Weber C:
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von Hundelshausen P, Koenen RR, Sack M, Mause SF, Adriaens W, Proudfoot AE, Hackeng TM, Weber C:
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Blood, 105(3):924-930
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Zhang J, McCrae KR:
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Koszalka P, Ozuyaman B, Huo Y, Zernecke A, Flogel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sevigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, Ley K, Zimmermann H, Godecke A, Schrader J:
Targeted disruption of cd73/ecto-5'-nucleotidase alters thromboregulation and augments vascular inflammatory response
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Lupke M, Rollwitz J, Simko M:
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Wottrich R, Diabate S, Krug HF:
Biological effects of ultrafine model particles in human macrophages and epithelial cells in mono- and co-culture
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Uray K, Medgyesi D, Hilbert A, Sarmay G, Gergely J, Hudecz F:
Synthesis and receptor binding of IgG1 peptides derived from the IgG Fc region
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Zhao XJ, Oliver P, Song K, Schurr J, Zhang Z, Kolls JK:
Chronic ethanol enhances ectodomain shedding in T cells and monocytes
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Safi H, Barnes PF, Lakey DL, Shams H, Samten B, Vankayalapati R, Howard ST:
IS6110 functions as a mobile, monocyte-activated promoter in Mycobacterium tuberculosis
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Turpaev K, Bouton C, Drapier JC:
Nitric oxide-derived nitrosating species and gene expression in human monocytic cells
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Szanto A, Benko S, Szatmari I, Balint BL, Furtos I, Ruhl R, Molnar S, Csiba L, Garuti R, Calandra S, Larsson H, Diczfalusy U, Nagy L:
Transcriptional Regulation of Human CYP27 Integrates Retinoid, Peroxisome Proliferator-Activated Receptor, and Liver X Receptor Signaling in Macrophages
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Grabiec A, Meng G, Fichte S, Bessler W, Wagner H, Kirschning CJ:
Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides
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Irschick EU, Sgonc R, Bock G, Wolf H, Fuchs D, Nussbaumer W, Gottinger W, Huemer HP:
Retinal pigment epithelial phagocytosis and metabolism differ from those of macrophages
Ophthalmic Res., 36(4):200-210
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Gerber A, Heimburg A, Reisenauer A, Wille A, Welte T, Buhling F:
Proteasome inhibitors modulate chemokine production in lung epithelial and monocytic cells
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Bounou S, Giguere JF, Cantin R, Gilbert C, Imbeault M, Martin G, Tremblay MJ:
The importance of virus-associated host ICAM-1 in human immunodeficiency virus type 1 dissemination depends on the cellular context
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Steeghs L, Tommassen J, Leusen JH, van de Winkel JG, van der Ley P:
Teasing apart structural determinants of 'toxicity' and 'adjuvanticity': implications for meningococcal vaccine development
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Ogawa K, Chen F, Kuang C, Chen Y:
Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a nuclear factor-kappaB site
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Fischer L, Steinhilber D, Werz O:
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Xu ZQ, Barrow WW, Suling WJ, Westbrook L, Barrow E, Lin YM, Flavin MT:
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis
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Rubic T, Trottmann M, Lorenz RL:
Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin
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Feisst C, Werz O:
Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin
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Takabayashi T, Shimizu S, Clark BD, Beinborn M, Burke JF, Gelfand JA:
Interleukin-1 upregulates anaphylatoxin receptors on mononuclear cells
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Neumeister B:
Intracellular Multiplication of Legionella Species and the Influence of Amoebae on Their Intracellular Growth in Human Monocytes: Mono Mac 6 Cells and Acanthamoeba castellanii as Suitable In Vitro Models
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Wieland H, Goetz F, Neumeister B:
Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes
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Demanet C, Mulder A, Deneys V, Worsham MJ, Maes P, Claas FH, Ferrone S:
Down-regulation of HLA-A and HLA-Bw6, but not HLA-Bw4, allospecificities in leukemic cells: an escape mechanism from CTL and NK attack?
Blood, 103:3122-3130
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Marshall AS, Willment JA, Lin HH, Williams DL, Gordon S, Brown GD:
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes
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Drexler HG, Quentmeier H, MacLeod RA:
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations
Leukemia, 18:227-232
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Zohlnhöfer D, Nuhrenberg TG, Neumann FJ, Richter T, May AE, Schmidt R, Denker K, Clauss MA, Schomig A, Baeuerle PA:
Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties
Mol Pharmacol., 65:880-889
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Schober A, Bernhagen J, Thiele M, Zeiffer U, Knarren S, Roller M, Bucala R, Weber C:
Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice
Circulation, 109:380-385
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Steinberger P, Majdic O, Derdak SV, Pfistershammer K, Kirchberger S, Klauser C, Zlabinger G, Pickl WF, Stockl J, Knapp W:
Molecular Characterization of Human 4Ig-B7-H3, a Member of the B7 Family with Four Ig-Like Domains
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Fraemohs L, Koenen RR, Ostermann G, Heinemann B, Weber C:
The functional interaction of the beta2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain
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Brandt R, Nawka M, Kellermann J, Salazar R, Becher D, Krantz S:
Nucleophosmin is a component of the fructoselysine-specific receptor in cell membranes of Mono Mac 6 and U937 monocyte-like cells
Biochim Biophys Acta (General Subjects) 1670: 132-136
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Gebbia JA, Coleman JL, Benach JL:
Selective induction of matrix metalloproteinases by Borrelia burgdorferi via toll-like receptor 2 in monocytes
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Vitale S, Schmid-Alliana A, Breuil V, Pomeranz M, Millet MA, Rossi B, Schmid-Antomarchi H.:
Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities
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Altmann A, Poeckel D, Fischer L, Schubert-Zsilavecz M, Steinhilber D, Werz O.:
Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes
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Mannonen L, Kamping E, Penttila T, Puolakkainen M:
IFN-gamma induced persistent Chlamydia pneumoniae infection in HL and Mono Mac 6 cells: characterization by real-time quantitative PCR and culture
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Kirchner S, Boldt S, Kolch W, Haffner S, Kazak S, Janosch P, Holler E, Andreesen R, Eissner G:
LPS resistance in monocytic cells caused by reverse signaling through transmembrane TNF (mTNF) is mediated by the MAPK/ERK pathway
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Wang R, Stephens J, Lacy MJ:
Characterization of monoclonal antibody HTA125 with specificity for human TLR4
Hybrid Hybridomics, 22:357-365
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Pham TN, Brown BL, Dobson PR, Richardson VJ:
Protein kinase C-eta (PKC-eta) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells
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Arkel YS, Ku DH, Thurston AL:
The effect of thalidomide on tissue factor activity in Mono Mac 6 cells and the relationship to tumor necrosis factor (TNF)-alpha-stimulated cells
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Schulz S, Birkenmeier G, Schagdarsurengin U, Wenzel K, Muller-Werdan U, Rehfeld D, Suss T, Kabisch A, Werdan K, Glaser C:
Role of LDL receptor-related protein (LRP) in coronary atherosclerosis
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Wahl C, Maier S, Marre R, Essig A.:
Chlamydia pneumoniae induces the expression of inhibitor of apoptosis 2 (c-IAP2) in a human monocytic cell line by an NF-kB-dependent pathway
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LeBouder E, Rey-Nores JE, Rushmere NK, Grigorov M, Lawn SD, Affolter M, Griffin GE, Ferrara P, Schiffrin EJ, Morgan BP, Labeta MO:
Soluble forms of toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk
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Barrow EW, Westbrook L, Bansal N, Suling WJ, Maddry JA, Parker WB, Barrow WW:
Antimycobacterial activity of 2-methyl-adenosine
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Fuentes L, Perez R, Nieto ML, Balsinde J, Balboa MA:
Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2
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Coleman JL, Benach JL:
The Urokinase Receptor Can Be Induced by Borrelia burgdorferi through Receptors of the Innate Immune System
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Baltus T, Weber KS, Johnson Z, Proudfoot AE, Weber C:
Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium
Blood, 102(6):1985-8
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Kato M, Khan S, Gonzalez N, O'Neill BP, McDonald KJ, Cooper BJ, Angel NZ, Hart DN:
Hodgkin's Lymphoma Cell Lines Express a Fusion Protein Encoded by Intergenically Spliced mRNA for the Multilectin Receptor DEC-205 (CD205) and a Novel C-type Lectin Receptor DCL-1
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Jimenez-Sainz MC, Fast B, Mayor F Jr, Aragay AM:
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The C2-like b-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1
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Ohata A, Usami M, Horiuchi T, Nagasawa K, Kinoshita K:
Release of (1-->3)-beta-D-Glucan from Depth-type Membrane Filters and Their In Vitro Effects on Proinflammatory Cytokine Production
Artif Organs., 27(8):728-35
2003
Abstract PubMed
Breuil V, Schmid-Antomarchi H, Schmid-Alliana A, Rezzonico R, Euller-Ziegler L, Rossi B:
The receptor activator of nuclear factor (NF)κB ligand (RANKL) is a new chemotactic factor for human monocytes
FASEB J, 17:1751-1753
2003
Abstract PubMed
Nilsen AM, Hagemann R, Eikas H, Egeberg K, Norkov T, Sundan A:
Reduction of IL-12 p40 production in activated monocytes after exposure to diesel exhaust particles
Int Arch Allergy Immunol, 131(3):201-8
2003
Abstract PubMed
Moesby L, Hansen EW, Christensen JD, Tommerup L, Nielsen C::
Endospores of B subtilis are pyrogenic and activate Mono Mac 6 cells: importance of the CD14 receptor.
Eur J Pharm Sci, 19(4):245-51
2003
Abstract PubMed
Sato K, Tomioka H, Sano C, Shimizu T, Sano K, Ogasawara K, Cai S, Kamei T:
Comparative antimicrobial activities of gatifloxacin, sitafloxacin and levofloxacin against Mycobacterium tuberculosis replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines
J Antimicrob Chemother 52(2): 199-203
2003
Abstract PubMed
Tonks AJ, Tonks A, Morris RH, Jones KP, Jackson SK:
Regulation of platelet-activating factor synthesis in human monocytes by dipalmitoyl phosphatidylcholine
J Leukoc Biol., 74(1):95-101
2003
Abstract PubMed
Van Der Ley P, Steeghs L:
Lessons from an LPS-deficient Neisseria meningitidis mutant
J Endotoxin Res., 9(2):124-8
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Abstract PubMed
Nakagawa Y, Murai T, Hasegawa C, Hirata M, Tsuchiya T, Yagami T, Haishima Y:
Endotoxin contamination in wound dressings made of natural biomaterials
J Biomed Mater Res., 66B(1):347-55
2003
Abstract PubMed
Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J, Tonks A:
Honey stimulates inflammatory cytokine production from monocytes
Cytokine, 21(5):242-247
2003
Abstract PubMed
Schmid B, Finnen MJ, Harwood JL, Jackson SK:
Acylation of lysophosphatidylcholine plays a key role in the response of monocytes to lipopolysaccharide
Eur J Biochem, 270(13):2782-2788
2003
Abstract PubMed
Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W:
Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells
Clin Cancer Res, 9(6):2140-2150
2003
Abstract PubMed
Klan N, Seuter S, Schnur N, Jung M, Steinhilber D:
Trichostatin A and structurally related histone deacetylase inhibitors induce 5-lipoxygenase promoter activity
Biol Chem, 384(5):777-85
2003
Abstract PubMed
Strobach D, Lorenz RL:
The bisphosphonate ibandronate stimulates reverse cholesterol transport out of monocytoid cells by enhanced ABCA1 transcription
Biochem Biophys Res Commun, 307(1):23-30
2003
Abstract PubMed
Lauber K, Bohn E, Kröber SM, Xiao Y, Blumenthal SG, Lindemann RK, Marini P, Wiedig C, Zobywalski A, Baksh S, Xu Y, Autenrieth IB, Schulze-Osthoff K, Belka K, Stuhler G, Wesselborg S:
Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal
Cell 113, 717-730
2003
Abstract PubMed
Zernecke A, Erl W, Fraemohs L, Lietz M, Weber C:
Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction
FASEB J. 17: 1099-1101
2003
Abstract PubMed
Vyas K, Brassard DL, DeLorenzo MM, Sun Y, Grace MJ, Borden EC, Leaman DW:
Biologic Activity of Polyethylene Glycol12000-Interferon-alpha2b Compared with Interferon-alpha2b: Gene Modulatory and Antigrowth Effects in Tumor Cells
J Immunother 26: 202-211
2003
Abstract PubMed
Tsutsumi-Ishii Y, Nagaoka I:
Modulation of Human beta-Defensin-2 Transcription in Pulmonary Epithelial Cells by Lipopolysaccharide-Stimulated Mononuclear Phagocytes Via Proinflammatory Cytokine Production
J Immunol 170: 4226-4236
2003
Abstract PubMed
Lee JY, Kim NA, Sanford A, Sullivan KE:
Histone acetylation and chromatin conformation are regulated separately at the TNF-alpha promoter in monocytes and macrophages
J Leukoc Biol 73: 862-871
2003
Abstract PubMed
Schwartz LB, Min HK, Ren S, Xia HZ, Hu J, Zhao W, Moxley G, Fukuoka Y:
Tryptase Precursors Are Preferentially and Spontaneously Released, Whereas Mature Tryptase Is Retained by HMC-1 Cells, Mono-Mac-6 Cells, and Human Skin-Derived Mast Cells
J Immunol 170: 5667-5673
2003
Abstract PubMed
Huo Y, Schober A, Forlow SB, Smith DF, Hyman MC, Jung S, Littman DR, Weber C, Ley K:
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
Nat Med 9: 61-67
2003
Abstract PubMed
May AE, Redecke V, Gruner S, Schmidt R, Massberg S, Miethke T, Ryba B, Prazeres Da Costa C, Schomig A, Neumann FJ:
Recruitment of Chlamydia pneumoniae-Infected Macrophages to the Carotid Artery Wall in Noninfected, Nonatherosclerotic Mice
Arterioscler Thromb Vasc Biol 23: 789-794
2003
Abstract PubMed
Zhao XJ, Marrero L, Song K, Oliver P, Chin SY, Simon H, Schurr JR, Zhang Z, Thoppil D, Lee S, Nelson S, Kolls JK:
Acute Alcohol Inhibits TNF-alpha Processing in Human Monocytes by Inhibiting TNF/TNF-alpha-Converting Enzyme Interactions in the Cell Membrane
J Immunol 170: 2923-2931
2003
Abstract PubMed
Weissgerber P, Faigle M, Northoff H, Neumeister B:
Investigation of mechanisms involved in phagocytosis of Legionella pneumophila by human cells
FEMS Microbiol Lett 219: 173-179
2003
Abstract PubMed
Langer T, Metzler M, Reinhardt D, Viehmann S, Borkhardt A, Reichel M, Stanulla M, Schrappe M, Creutzig U, Ritter J, Leis T, Jacobs U, Harbott J, Beck JD, Rascher W, Repp R:
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: Almost identical MLL breakpoints in therapy-related AML after treatment without etoposides
Genes Chromosomes Cancer 36: 393-401
2003
Abstract PubMed
Fueller M, Wang de A, Tigyi G, Siess W:
Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate
Cell Signal 15: 367-375
2003
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Poole S, Mistry Y, Ball C, Gaines Das RE, Opie LP, Tucker G, Patel M:
A rapid 'one-plate' in vitro test for pyrogens
J Immunol Methods 274: 209-220
2003
Abstract PubMed
Shatrov VA, Sumbayev VV, Zhou J, Bruene B:
Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1a (HIF-1a) accumulation via redox-dependent mechanisms
Blood 101: 4847-4849
2003
Abstract PubMed
Neurauter G, Wirleitner B, Laich A, Schennach H, Weiss G, Fuchs D:
Atorvastatin suppresses interferon-gamma -induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines
Clin Exp Immunol 131: 264-267
2003
Abstract PubMed
Burkert E, Szellas D, Radmark O, Steinhilber D, Werz O:
Cell type-dependent activation of 5-lipoxygenase by arachidonic acid
J Leukoc Biol 73: 191-200
2003
Abstract PubMed
Klan N, Steinhilber D:
Transient transfection of the human myeloid cell line Mono Mac 6 using electroporation
Biotechniques 34: 142-147
2003
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Bufler P, Schmidt B, Schikor D, Bauernfeind A, Crouch EC, Griese M:
Surfactant Protein A and D Differently Regulate the Immune Response to Nonmucoid Pseudomonas aeruginosa and Its Lipopolysaccharide
Am J Respir Cell Mol Biol 28: 249-256
2003
Abstract PubMed
Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE:
Regulation of Tumor Necrosis Factor Alpha Gene Expression by Mycobacteria Involves the Assembly of a Unique Enhanceosome Dependent on the Coactivator Proteins CBP/p300
Mol Cell Biol 23: 526-533
2003
Abstract PubMed
Greiner A, Lautwein A, Overkleeft HS, Weber E, Driessen C:
Activity and subcellular distribution of cathepsins in primary human monocytes
J Leukoc Biol 73: 235-242
2003
Abstract PubMed
Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C, Schnittger S, Kelly LM, Gilliland DG, Hiddemann W:
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
Blood 101: 1494-1504
2003
Abstract PubMed
Håversen L, Ohlsson BG, Hahn-Zoric M, Hanson LÅ, Mattsby-Baltzer I:
Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kB
Cell Immunol 220: 83-95
2002
Abstract PubMed
Kaehler CM, Kaufmann G, Kaehler ST, Wiedermann CJ:
The neuropeptide secretoneurin stimulates adhesion of human monocytes to arterial and venous endothelial cells in vitro
Regul Pept 110: 65-73
2002
Abstract PubMed
Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V:
Interactions between ultrafine particles and transition metals in vivo and in vitro
Toxicol Appl Pharmacol 184: 172-179
2002
Abstract PubMed
Neumeister B, Faigle M, Lauber K, Northoff H, Wesselborg S:
Legionella pneumophila induces apoptosis via the mitochondrial death pathway
Microbiology 148: 3639-3650
2002
Abstract PubMed
Klein CA, Seidl S, Petat-Dutter K, Offner S, Geigl JB, Schmidt-Kittler O, Wendler N, Passlick B, Huber RM, Schlimok G, Baeuerle PA, Riethmuller G:
Combined transcriptome and genome analysis of single micrometastatic cells
Nat Biotechnol 20: 387-392
2002
Abstract PubMed
Tsubery H, Ofek I, Cohen S, Eisenstein M, Fridkin M:
Modulation of the hydrophobic domain of polymyxin B nonapeptide: effect on outer-membrane permeabilization and lipopolysaccharide neutralization
Mol Pharmacol 62: 1036-1042
2002
Abstract PubMed
Danz H, Stoyanova S, Thomet OA, Simon HU, Dannhardt G, Ulbrich H, Hamburger M:
Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis
Planta Med 68: 875-880
2002
Abstract PubMed
Stroh C, Cassens U, Samraj AK, Sibrowski W, Schulze-Osthoff K, Los M:
The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells
FASEB J 16: 1651-1653
2002
Abstract PubMed
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J:
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
J Exp Med 196: 1017-1024
2002
Abstract PubMed
Schober A, Manka D, von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C:
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury
Circulation 106: 1523-1529
2002
Abstract PubMed
Natarajan M, Aravindan N, Meltz ML, Herman TS:
Post-translational modification of I-kappa B alpha activates NF-kappa B in human monocytes exposed to 56Fe ions
Radiat Environ Biophys 41: 139-144
2002
Abstract PubMed
Schulte CE, Lindern Mv M, Steinlein P, Beug H, Wiedemann LM:
MLL-ENL cooperates with SCF to transform primary avian multipotent cells
EMBO J 21: 4297-4306
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Abstract PubMed
Vandenplas ML, Carlson RW, Jeyaretnam BS, McNeill B, Barton MH, Norton N, Murray TF, Moore JN:
Rhizobium sin-1 LPS prevents enteric LPS-induced cytokine production by mono Mac 6 cells
J Biol Chem 277: 41811-41816
2002
Abstract PubMed
Werz O, Bürkert E, Fischer L, Szellas D, Dishart D, Samuelsson B, Rådmark O, Steinhilber D:
Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes
FASEB J 16: 1441-1443
2002
Abstract PubMed
May AE, Schmidt R, Kanse SM, Chavakis T, Stephens RW, Schomig A, PreissnerKT, Neumann FJ:
Urokinase Receptor Surface Expression Regulates Monocyte Adhesion in Acute Myocardial Infarction
Blood 100: 3611-3617
2002
Abstract PubMed
Kerkhoff C, Hofmann HA, Vormoor J, Melkonyan H, Roth J, Sorg C, Klempt M:
Binding of two nuclear complexes to a novel regulatory element within the human S100A9 promoter drives the S100A9 gene expression
J Biol Chem 277: 41879-41887
2002
Abstract PubMed
Cervino AC, Lakiss S, Sow O, Bellamy R, Beyers N, Hoal-Van Helden E, Van Helden P, McAdam KP, Hill AV:
Fine mapping of a putative tuberculosis-susceptibility locus on chromosome 15q11-13 in African families
Hum Mol Genet 11: 1599-1603
2002
Abstract PubMed
Soto D, Malmsten C, Blount JL, Muilenburg DJ, Caughey GH:
Genetic deficiency of human mast cell a-tryptase
Clin Exp Allergy 32: 1000-1006
2002
Abstract PubMed
Wieland H, Faigle M, Lang F, Northoff H, Neumeister B:
Regulation of the Legionella mip-promotor during infection of human monocytes
FEMS Microbiol Lett 212: 127-132
2002
Abstract PubMed
Burkert E, Radmark O, Steinhilber D, Werz O:
Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent
Biochem Biophys Res Commun 295: 985-991
2002
Abstract PubMed
Triantafilou M, Miyake K, Golenbock DT, Triantafilou K:
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
J Cell Sci 115: 2603-2611
2002
Abstract PubMed
Wolfert MA, Murray TF, Boons GJ, Moore JN:
The origin of the synergistic effect of muramyldipeptide with endotoxin and peptidoglycan
J Biol Chem 277: 39179-39186
2002
Abstract PubMed
Nakagawa Y, Maeda H, Murai T:
Evaluation of the in vitro pyrogen test system based on proinflammatory cytokine release from human monocytes: comparison with a human whole blood culture test system and with the rabbit pyrogen test
Clin Diagn Lab Immunol 9: 588-597
2002
Abstract PubMed
Haehnel V, Schwarzfischer L, Fenton MJ, Rehli M:
Transcriptional regulation of the human toll-like receptor 2 gene in monocytes and macrophages
J Immunol 168: 5629-5637
2002
Abstract PubMed
Van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D:
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-kappaB transcription factors
Hum Mol Genet 11:1281-1289
2002
Abstract PubMed
Kwakkenbos MJ, Chang GW, Lin HH, Pouwels W, de Jong EC, van Lier RA, Gordon S, Hamann J:
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells
J Leukoc Biol 71: 854-862
2002
Abstract PubMed
Swinney DC, Xu YZ, Scarafia LE, Lee I, Mak AY, Gan QF, Ramesha CS, Mulkins MA, Dunn J, So OY, Biegel T, Dinh M, Volkel P, Barnett J, Dalrymple SA, Lee S, Huber M:
A small molecule ubiquitination inhibitor blocks NF-kappa B-dependent cytokine expression in cells and rats
J Biol Chem 277: 23573-23581
2002
Abstract PubMed
Lehmann T, Murphy C, Zahra DG, Handel ML:
Reduction of tumor necrosis factor induced nuclear factor-kappaB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants
J Rheumatol 29: 787-795
2002
Abstract PubMed
Natarajan M, V V, Szilagyi M, Roldan FN, Meltz ML:
NF-kappaB DNA-binding activity after high peak power pulsed microwave (8.2 GHz) exposure of normal human monocytes.
Bioelectromagnetics 23: 271-277
2002
Abstract PubMed
Sato K, Tomioka H, Shimizu T, Gonda T, Ota F, Sano C:
Type II Alveolar Cells Play Roles in Macrophage-Mediated Host Innate Resistance to Pulmonary Mycobacterial Infections by Producing Proinflammatory Cytokines
J Infect Dis 185: 1139-1147
2002
Abstract PubMed
Mack M, Pfirstinger J, Weber C, Weber KS, Nelson PJ, Rupp T, Maletz K, Bruhl H, Schlondorff D:
Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES-dependent firm adhesion of leukocytes
Eur J Immunol 32: 1012-1020
2002
Abstract PubMed
Kroesen B-J, McLaughlin P M J, Schuilenga-Hut P H L, Jacobs S C, Molema G, Helfrich W, De Leij L F M H:
Tumor-targeted immune complex formation: Effects on myeloid cell activation and tumor-directed immune cell migration
Int J of Cancer 98: 857-863
2002
Abstract PubMed
Burkert E, Radmark O, Samuelsson B, Steinhilber D, Werz O:
Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes
J Leukoc Biol 71: 477-486
2002
Abstract PubMed
Werz O, Szellas D, Steinhilber D, Radmark O:
Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2)
J Biol Chem; 277(17):14793-800
2002
Abstract PubMed
Tomioka H, Sato K, Sano C, Sano K, Shimizu T:
Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells.
Antimicrob Agents Chemother 46: 519-521
2002
Abstract PubMed
Lee HA, Hughes DA:
Alpha-lipoic acid modulates NF-kappaB activity in human monocytic cells by direct interaction with DNA
Exp Gerontol 37: 401-410
2002
Abstract PubMed
Burke B, Tang N, Corke KP, Tazzyman D, Ameri K, Wells M, Lewis CE:
Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy
J Pathol 196: 204-212
2002
Abstract PubMed
Jostarndt K, Gellert N, Rubic T, Weber C, Kuhn H, Johansen B, Hrboticky N, Neuzil J:
Dissociation of Apoptosis Induction and CD36 Upregulation by Enzymatically
Biochem Biophys Res Commun 290: 988-93
2002
Abstract PubMed
Sing A, Roggenkamp A, Geiger AM, Heesemann J.:
Yersinia enterocolitica Evasion of the Host Innate Immune Response by V Antigen-Induced IL-10 Production of Macrophages Is Abrogated in IL-10-Deficient Mice
J Immunol 168: 1315-21
2002
Abstract PubMed
Burkart V, Kim YE, Hartmann B, Ghiea I, Syldath U, Kauer M, Fingberg W, Hanifi-Moghaddam P, Muller S, Kolb H.:
Cholera Toxin B Pretreatment of Macrophages and Monocytes Diminishes Their Proinflammatory Responsiveness to Lipopolysaccharide
J Immunol 168: 1730-1737
2002
Abstract PubMed
Uhl J, Klan N, Rose M, Entian KD, Werz O, Steinhilber D:
The 5-lipoxygenase promoter is regulated by DNA methylation
J Biol Chem., 277(6):4374-4379
2002
Abstract PubMed
Salazar R, Brandt R, Krantz S:
Binding of Amadori glucose-modified albumin by the monocytic cell line MonoMac 6 activates protein kinase C varepsilon protein tyrosine kinases and the transcription factors AP-1 and NF-kappaB
Glycoconj J 18: 769-777
2001
Abstract PubMed
Weber KS, Weber C, Ostermann G, Dierks H, Nagel W, Kolanus W:
Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines
Curr Biol 11: 1969-1974
2001
Abstract PubMed
Randow F, Seed B:
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
Nat Cell Biol 3: 891-896
2001
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Zernecke A, Weber KS, Weber C:
Combined modulation of the mesangial machinery for monocyte recruitment by inhibition of NF-kappaB
Am J Physiol Cell Physiol 281: C1881-C1888
2001
Abstract PubMed
Bonder CS, Hart PH, Davies KV, Burkly LC, Finlay-Jones JJ, Woodcock JM:
Characterization of IL-4 receptor components expressed on monocytes and monocyte-derived macrophages: variation associated with differential signaling by IL-4
Growth Factors 19: 207-218
2001
Abstract PubMed
Pereira HA:
Cationic antimicrobial protein of Mr 37 kDa: a multifunctional inflammatory protein
Chin Med J (Engl) 114: 9-13
2001
Abstract PubMed
Wahl C, Oswald F, Simnacher U, Weiss S, Marre R, Essig A:
Survival of Chlamydia pneumoniae-Infected Mono Mac 6 Cells Is Dependent on NF-kappaB Binding Activity
Infect Immun 69:7039-7045
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Elms J, Beckett PN, Griffin P, Curran AD:
Mechanisms of isocyanate sensitisation. An in vitro approach
Toxicol In Vitro 15: 631-634
2001
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Schupp P, Steube K, Meyer C, Proksch P:
Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm
Cancer Lett 174:165-172
2001
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LeVan TD, Bloom JW, Bailey TJ, Karp CL, Halonen M, Martinez FD, Vercelli D:
A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
J Immunol 167:5838-5844
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Abstract PubMed
Stoyanova E, Tesch A, Armstrong VW, Wieland E:
Enzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins
Clin Biochem 34:483-490
2001
Abstract PubMed
Triantafilou K, Triantafilou M, Dedrick RL:
A CD14-independent LPS receptor cluster
Nat Immunol 2:338-345
2001
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Skovronsky DM, Fath S, Lee VM, Milla ME:
Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques
J Neurobiol 49:40-46
2001
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Ogbourne SM, Antalis TM:
Characterisation of PAUSE-1, a powerful silencer in the human plasminogen activator inhibitor type 2 gene promoter
Nucleic Acids Res 29:3919-3927
2001
Abstract PubMed
van der Ley P, Steeghs L, Hamstra HJ, ten Hove J, Zomer B, van Alphen L:
Modification of lipid A biosynthesis in Neisseria meningitidis lpxL mutants: influence on lipopolysaccharide structure, toxicity, and adjuvant activity
Infect Immun 69:5981-5990
2001
Abstract PubMed
Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K:
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium
J Clin Invest 108:1307-1314
2001
Abstract PubMed
Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD:
Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases
J Pharmacol Exp Ther 298:900-908
2001
Abstract PubMed
Brown DM, Wilson MR, MacNee W, Stone V, Donaldson K:
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines
Toxicol Appl Pharmacol 175:191-199
2001
Abstract PubMed
Neumeister B, Bach V, Faigle M, Northoff H:
Induction of iNOS in human monocytes infected with different Legionella species
FEMS Microbiol Lett 202: 31-38
2001
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Dinkelmann S, Rohlke W, Meinert H, Northoff H:
A system establishment compatibility profiles for artificial oxygen carriers and other substances
Artif Cells Blood Substit Immobil Biotechnol 29: 57-70
2001
Abstract PubMed
Danz H, Stoyanova S, Wippich P, Brattstrom A, Hamburger M:
Identification and isolation of the cyclooxygenase-2 inhibitory principle in Isatis tinctoria
Planta Med 67: 411-416
2001
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Ross HL, Nonnemacher MR, Hogan TH, Quiterio SJ, Henderson A, McAllister JJ, Krebs FC, Wigdahl B:
Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage
J Virol 75: 1842-1856
2001
Abstract PubMed
Vidal VF, Casteran N, Riendeau CJ, Kornfeld H, Darcissac EC, Capron A, Bahr GM:
Macrophage stimulation with Murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPbeta and STAT1: role of CD14 and Toll-like receptors 2 and 4
Eur J Immunol 31: 1962-1971
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Woltman AM, de Fijter JW, Kamerling SW, van Der Kooij SW, Paul LC, Daha MR, van Kooten C:
Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages
Blood 98: 174-180
2001
Abstract PubMed
Tonks A, Cooper RA, Price AJ, Molan PC, Jones KP:
Stimulation of tnf-alpha release in monocytes by honey
Cytokine 14: 240-242
2001
Abstract PubMed
Yang Z, Tao T, Raftery MJ, Youssef P, Di Girolamo N, Geczy CL:
Proinflammatory properties of the human S100 protein S100A12
J Leukoc Biol 69: 986-994
2001
Abstract PubMed
von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, Ley K, Weber C:
RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium
Circulation 103: 1772-1777
2001
Abstract PubMed
Haishima Y, Murai T, Nakagawa Y, Hirata M, Yagami T, Nakamura A:
Chemical and biological evaluation of endotoxin contamination on natural rubber latex products
J Biomed Mater Res (Part A) 55: 424-32
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Abstract PubMed
Ali SA, Stoeva S, Abbasi A, Alam JM, Kayed R, Faigle M, Neumeister B, Voelter W:
Isolation, structural, and functional characterization of an apoptosis-inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom
Arch Biochem Biophys 384: 216-226
2001
Abstract PubMed
Lee JY, Sullivan KE:
Gamma interferon and lipopolysaccharide interact at the level of transcription to induce tumor necrosis factor alpha expression
Infect Immun 69: 2847-2852
2001
Abstract PubMed
Tonks A, Morris RH, Price AJ, Thomas AW, Jones KP, Jackson SK:
Dipalmitoylphosphatidylcholine modulates inflammatory functions of monocytic cells independently of mitogen activated protein kinases
Clin Exp Immunol 124: 86-94
2001
Abstract PubMed
Gorbacheva VY, Faundez G, Godfrey HP, Cabello FC:
Restricted growth of ent- and tonB mutants of Salmonella enterica serovar Typhi in human Mono Mac 6 monocytic cells
FEMS Microbiol Lett 196: 7-11
2001
Abstract PubMed
Werz O, Klemm J, Samuelsson B, Radmark O:
Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes
Blood 97: 2487-2495
2001
Abstract PubMed
Musso T, Deaglio S, Franco L, Calosso L, Badolato R, Garbarino G, Dianzani U, Malavasi F:
CD38 expression and functional activities are up-regulated by IFN-g on human monocytes and monocytic cell lines
J Leukoc Biol 69: 605-612
2001
Abstract PubMed
Vaday GG, Schor H, Rahat MA, Lahat N, Lider O:
Transforming growth factor-beta suppresses tumor necrosis factor alpha-induced matrix metalloproteinase-9 expression in monocytes
J Leukoc Biol 69: 613-621
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Daulouède S, Bouteille B, Moynet D, De Baetselier P, Courtois P, Lemesre JL, Buguet A, Cespuglio R, Vincendeau P:
Human macrophage tumor necrosis factor TNF-alpha production induced by Trypanosoma brucei gambiense and the role of TNF-alpha in parasite control
J Infect Dis 183: 988-991
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Abstract PubMed
Zhang Z, Bagby GJ, Stoltz D, Oliver P, Schwarzenberger PO, Kolls JK:
Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-alpha production in human monocytic cells
Alcohol Clin Exp Res 25: 444-449
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Abstract PubMed
Rinker KD, Prabhakar V, Truskey GA:
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Biophys J 80: 1722-1732
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Sato K, Akaki T, Shimizu T, Sano C, Ogasawara K, Tomioka H:
Invasion and intracellular growth of Mycobacterium tuberculosis and Mycobacterium avium complex adapted to intramacrophagic environment within macrophages and type II alveolar epithelial cells
Kekkaku 76: 53-57
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Cambien B, Pomeranz M, Millet MA, Rossi B, Schmid-Alliana A:
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Blood 97(2): 359-366
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Cambien B, Pomeranz M, Schmid-Antomarchi H, Millet MA, Breittmayer V, Rossi B, Schmid-Alliana A:
Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion
Blood 97 (7): 2031-2037
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Abstract PubMed
Fessele S, Boehlk S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D, Nelson PJ:
Molecular and in silico characterization of a promoter module and C/EBP element that mediate LPS-induced RANTES/CCL5 expression in monocytic cells
FASEB J 15: 577-579
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Min HK, Kambe N, Schwartz LB:
Human mouse mast cell protease 7-like tryptase genes are pseudogenes
J Allergy Clin Immunol 107: 315-321
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Ulanova M, Tarkowski A, Hahn-Zoric M, Hanson LA:
The Common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism
Infect Immun 69:1151-1159
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Abstract PubMed
Jonas D, Engels I I, Friedhoff C, Spitzmuller B, Daschner FD, Frank U:
Efficacy of moxifloxacin, trovafloxacin, clinafloxacin and levofloxacin against intracellular Legionella pneumophila
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Fettes PS, Susa M, Hacker J, Marre R:
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Int J Med Microbiol 290: 239-250
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Howie S, Ramage R, Hewson T:
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Am J Respir Crit Care Med 162 (4): S141-S145
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Rodenburg RJ, Ganga A, van Lent PL, van de Putte LB, van Venrooij WJ:
The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis
Arthritis Rheum 43: 1941-1950
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Scarafia LE, Winter A, Swinney DC:
Quantitative expression analysis of the cellular specificity of HECT-domain ubiquitin E3 ligases
Physiol Genomics 4: 147-153
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Lehmann T, Nguyen LQ, Handel ML:
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J Rheumatol 27: 2769-2776
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Udalova IA, Richardson A, Denys A, Smith C, Ackerman H, Foxwell B, Kwiatkowski D:
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Mol Cell Biol 20: 9113-9119
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Vaday GG, Hershkoviz R, Rahat MA, Lahat N, Cahalon L, Lider O:
Fibronectin-bound TNF-alpha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis
J Leukoc Biol 68: 737-747
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Morris RHK, Price AJ, Tonks A, Jackson SK, Jones KP:
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Cytokine 12: 1717-1719
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Pedraza C, Geberhiwot T, Ingerpuu S, Assefa D, Wondimu Z, Kortesmaa J, Tryggvason K, Virtanen I, Patarroyo M:
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J Immunol 165: 5831-5838
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Ahmed ST, Ivashkiv LB:
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J Immunol 165: 5227-5237
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Legionella species of different human prevalence induce different rates of apoptosis in human monocytic cells
APMIS 2000 108: 398-408
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Gerhardt H, Walz MJ, Faigle M, Northoff H, Wolburg H, Neumeister B:
Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila
FEMS Microbiol Lett 192: 145-152
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Buehling F, Ittenson A, Kaiser D, Tholert G, Hoffmann B, Reinhold D, Ansorge S, Welte T:
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Immunol Lett 71:185-190
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Suling WJ, Seitz LE, Pathak V, Westbrook L, Barrow EW, Zywno-Van-Ginkel S, Reynolds RC, Piper JR, Barrow WW:
Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase
Antimicrob Agents Chemother, 44: 2784-2793
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Abstract PubMed
Brown DM, Stone V, Findlay P, MacNee W, Donaldson K:
Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components
Occup Environ Med , 57: 685-691
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Abstract PubMed
Jonas D, Engels I, Daschner FD, Frank U:
The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo
J Antimicrob Chemother, 46: 385-390
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Moesby L, Hansen EW, Christensen JD:
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J Clin Pharm Ther, 25: 283-289
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Pan Z, Zhou L, Hetherington CJ, Zhang DE:
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Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ:
DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis
Hum Mol Genet; 9: 1671-1679
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Steube KG, Meyer C, Drexler HG:
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Cytokine 12: 1236-1239
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Triantafilou M, Triantafilou K, Fernandez N:
Rough and smooth forms of fluorescein-labelled bacterial endotoxin exhibit CD14/LBP dependent and independent binding that is influencedby endotoxin concentration
Eur J Biochem 267: 2218-2226
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Udalova IA, Vidal V, Scragg IG, Kwiatkowski D:
Direct Evidence for Involvement of NF-kappaB in Transcriptional Activation of Tumor Necrosis Factor by a Spirochetal Lipoprotein
Infect Immun 68: 5447-5449
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Straif D, Werz O, Kellner R, Bahr U, Steinhilber D:
Glutathione peroxidase-1 but not -4 is involved in the regulation of cellular 5-lipoxygenase activity in monocytic cells
Biochem J 349: 455-461
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Burgermeister E, Pessara U, Tibes U, Kuster A, Heinrich PC, Scheuer WV:
Inhibition of cytosolic phospholipase A(2) attenuates activation of mitogen-activated protein kinases in human monocytic cells
Eur J Pharmacol 388: 195-208
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Moesby L, Hansen EW, Christensen JD:
Ultrasonication of pyrogenic microorganisms improves the detection of pyrogens in the Mono Mac 6 assay
Eur J Pharm Sci 11: 51-57
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Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE:
A lipopolysaccharide-specific enhancer complex involving ets, elk-1, sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter In vivo
Mol Cell Biol 20: 6084-6094
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Abstract PubMed
Zhang Z, Cork J, Ye P, Lei D, Schwarzenberger PO, Summer WR, Shellito JE, Nelson S, Kolls JK:
Inhibition of TNF-alpha processing and TACE-mediated ectodomain shedding by ethanol
Leukoc Biol 67:856-862
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Eissner G, Kirchner S, Lindner H, Kolch W, Janosch P, Grell M, Scheurich P, Andreesen R, Holler E:
Reverse Signaling Through Transmembrane TNF Confers Resistance to Lipopolysaccharide in Human Monocytes and Macrophages
J Immunol 164: 6193-6198
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Fearns C, Kline L, Gram H, Di Padova F, Zurini M, Han J, Ulevitch RJ:
Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli
J Leukoc Biol 67: 705-711
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Werz O, Wiesinger H, Steinmeyer A, Steinhilber D:
New vitamin D receptor agonists with decreased metabolic stability
Biochem Pharmacol, 59:1597-1601
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Werz O, Klemm J, Samuelsson B, Radmark O:
5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
Proc Natl Acad Sci U S A 97: 5261-5266
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Dankesreiter S, Hoess A, Schneider-Mergener J, Wagner H, Miethke T:
Synthetic endotoxin-binding peptides block endotoxin- triggered TNF-alpha production by macrophages In vitro and In vivo and prevent endotoxin-mediated toxic shock
J Immunol 164:4804-4811
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van Aken BE, Jansen J, van Deventer SJ, Reitsma PH:
Elevated levels of homocysteine increase IL-6 production in monocytic Mono Mac 6 cells
Blood Coagul Fibrinolysis 11:159-164
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Liew MA, McPhun V, Baker MS:
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Cytometry 40:32-41
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Boehlk S, Fessele S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D, Nelson PJ:
ATF and Jun transcription factors, acting through an Ets / CRE promoter module, mediate lipopolysaccharide inducibility of the chemokine RANTES in monocytic Mono Mac 6 cells
Eur J Immunol 30:1102-1112
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Abstract PubMed
Zhang Z, Kolls JK, Oliver P, Good D, Schwarzenberger PO, Joshi MS, Ponthier JL, Lancaster JR:
Activation of Tumor Necrosis Factor-a Converting Enzyme-mediated Ectodomain Shedding by Nitric Oxide
J Biol Chem 275(21):15839-44.
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Eissner G, Lindner H, Konur A, Kreutz M, Andreesen R, Holler E:
Naive monocytes can trigger transendothelial migration of peripheral blood cells through the induction of endothelial tumour necrosis factor-alpha
Scand J Immunol 51: 251-261
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Stone V, Tuinman M, Vamvakopoulos JE, Shaw J, Brown D, Petterson S, Faux SP, Borm P, MacNee W, Michaelangeli F, Donaldson K:
Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black
Eur Respir J 15: 297-303
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Neumeister B, Reiff G, Faigle M, Dietz K, Northoff H, Lang F:
Influence of Acanthamoeba castellanii on Intracellular Growth of Different Legionella Species in Human Monocytes
Appl Environ Microbiol 66: 914-919
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Jones BG, Gumbleton M, Kellaway IW, Dickinson PA:
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Int J Pharm 195: 17-23
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Scragg IG, Kwiatkowski D, Vidal V, Reason A, Paxton T, Panico M, Dell A, Morris H:
Structural characterization of the inflammatory moiety of a variable major lipoprotein of Borrelia recurrentis
J Biol Chem 275: 937-941
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Tomioka, H., Sato, K., Kajitani, H., Akaki, T., Shishido, S:
Comparative Antimicrobial Activities of the Newly Synthesized Quinolone WQ-3034, Levofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium Complex
Antimicrob Agents Chemother 44: 283-286
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Abstract PubMed
Heidenthal, A.K., Weber, P.C., Lottspeich, F., Hrboticky, N:
The Binding in Vitro of Modified LDL to the Intermediate Filament Protein Vimentin
Biochem Biophys Res Commun 267: 49-53
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Sironi M, Guglielmotti A, Polentarutti N, Fioretti F, Milanese C, Romano M, Vigini C, Coletta I, Sozzani S, Bernasconi S, Vecchi A, Pinza M, Mantovani A:
A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1
Eur Cytokine Netw 10: 437-442
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Riehemann K, Behnke B, Schulze-Osthoff K:
Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB
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Burkart V, Kim Y, Kauer M, Kolb H:
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Bohnenstengel FI, Steube KG, Meyer C, Quentmeier H, Nugroho BW, Proksch P:
1H-cyclopenta[b]benzofuran lignans from Aglaia species inhibit cell proliferation and alter cell cycle distribution in human monocytic leukemia cell lines
Z Naturforsch [C] 54:1075-1083
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Abstract PubMed
Haerle D, Radmark O, Samuelsson B, Steinhilber D:
Transcriptional and posttranscriptional regulation of 5-lipoxygenase mRNA expression in the human monocytic cell line Mono Mac 6 by transforming growth factor-beta and 1,25-dihydroxyvitamin D3
Adv Exp Med Biol 469: 105-111
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Valen, G., Erl, W., Eriksson, P., Wuttge, D., Paulsson, G., Hansson, G.K:
Hydrogen peroxide induces mRNA for tumour necrosis factor alpha in human endothelial cells
Free Radic Res 31: 503-512
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Abstract PubMed
Watts, A.D., Hunt, N.H., Madigan, M.C., Chaudhri, G:
Soluble TNF-alpha receptors bind and neutralize over-expressed transmembrane TNF-alpha on macrophages, but do not inhibit its processing
J Leukoc Biol 66:1005-1013
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Abstract PubMed
van Zandbergen, G., Westerhuis, R., Mohamad, N.K., van De Winkel, J.G., Daha, M.R., van Kooten, C.:
Crosslinking of the Human Fc Receptor for IgA (FcalphaRI/CD89) Triggers FcR gamma-Chain-Dependent Shedding of Soluble CD89
J Immunol 163: 5806-5812
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Abstract PubMed
Moesby L., Jensen S., Hansen E.W., Christensen J.D.:
A comparative study of Mono Mac 6 cells, isolated mononuclear cells and Limulus amoebocyte lysate assay in pyrogen testing
Int J Pharm, 191:141-149
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Pan, Z., Hetherington, C.J., Zhang, D.E:
CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development
J Biol Chem, 274: 23242-2328
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Lorenzen, D.R., Dux, F., Wolk, U., Tsirpouchtsidis, A., Haas, G., Meyer, T.F:
Immunoglobulin A1 protease, an exoenzyme of pathogenic neisseriae, is a potent inducer of proinflammatory cytokines
J Exp Med, 190: 1049-1058
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Trautmann, M., Heinemann, M., Moricke, A., Seidelmann, M., Lorenz, I., Berger, D., Steinbach, G., Schneider, M:
Endotoxin release due to ciprofloxacin measured by three different methods
J Chemother, 11: 248-254
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Grone, H.J., Weber, C., Weber, K.S., Grone, E.F., Rabelink, T., Klier, C.M., Wells, T.N., Proudfood, A.E., Schlondorff, D., Nelson, P.J:
Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment
FASEB J, 13: 1371-1383
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Vraetz, T., Ittel, T.H., van Mackelenbergh, M.G., Heinrich, P.C., Sieberth, H.G., Graeve, L:
Regulation of beta2-microglobulin expression in different human cell lines by proinflammatory cytokines
Nephrol Dial Transplant, 14: 2137-2143
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Scragg, I.G., Hensmann, M., Bate, C.A., Kwiatkowski, D:
Early cytokine induction by Plasmodium falciparum is not a classical endotoxin-like process
Eur J Immunol, 29: 2636-2644
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Bakker, A.B., Baker, E., Sutherland, G.R., Phillips, J.H., Lanier, L.L:
Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells
Proc Natl Acad Sci U S A, 17: 9792-9796
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Penton-Rol, G., Cota, M., Polentarutti, N., Luini, W., Bernasconi, S., Borsatti, A., Sica, A., LaRosa, G.J., Sozzani, S., Poli, G., Mantovani, A:
Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones
J. Immunol., 163: 3524-3529
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Abstract PubMed
Steube, K.G., Meyer, C., Drexler, H.G:
Constitutive protein expression of monocyte chemotactic protein-1 (MCP-1) by myelomonocytic cell lines and regulation of the secretion by anti- and proinflammatory stimuli
Leuk. Res., 23:843-849
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Abstract PubMed
Sato, K., Ogasawara, K., Akaki, T., Tomioka, H:
MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines
Kekkaku, 74: 571-577
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Abstract PubMed
Curiel, R.E., Garcia, C.S., Rottschafer, S., Bosco, M.C., Espinoza-Delgado, I:
Enhanced B7-2 Gene Expression by Interferon- in Human Monocytic Cells Is Controlled Through Transcriptional and Posttranscriptional Mechanisms
Blood, 94: 1782-1789
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Jansen, M., Reinhard, J.F. Jr:
Interferon response heterogeneity: activation of a pro-inflammatory response by interferon alpha and beta. A possible basis for diverse responses to interferon beta in MS.
J. Leukoc. Biol., 65:439-443
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Berg, J., Fellier, H., Christoph, T., Grarup, J., Stimmeder, D:
The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)-1/-2, inducible nitric oxide synthase (iNOS), and the formation of interleukin (IL)-6 in vitro
Inflamm. Res., 48:369-379
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Weber, C., Draude, G., Weber, K.S., Wubert, J., Lorenz, R.L., Weber, P.C:
Downregulation by tumor necrosis factor-alpha of monocyte CCR2 expression and monocyte chemotactic protein-1-induced transendothelial migration is antagonized by oxidized low-density lipoprotein: a potential mechanism of monocyte retention in atherosclero
Atherosclerosis145:115-123
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Abstract PubMed
Musso, T., Calosso, L., Zucca, M., Millesimo, M., Ravarino, D., Giovarelli, M., Malavasi, F., Ponzi, A.N., Paus, R., Bulfone-Paus, S:
Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15
Blood 93: 3531-3539
1999
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Iwama, A., Pan, J., Zhang, P., Reith, W., Mach, B., Tenen, D.G., Sun, Z.:
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains
Mol Cell Biol, 19:3940-3950
1999
Abstract PubMed
Weber, K.S., Draude, G., Erl, W., de Martin, R., Weber, C.:
Monocyte arrest and transmigration on inflamed endothelium in shear flow is inhibited by adenovirus-mediated gene transfer of IkappaB-alpha
Blood, 93:3685-3693
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Abstract PubMed
Karimi, K., Gemmill, T.R., Lennartz, M.R.:
Protein kinase C and a calcium-independent phospholipase are required for IgG-mediated phagocytosis by Mono-Mac-6 cells
J. Leukoc. Biol. 65: 854-862
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Abstract PubMed
Knight, J.C., Udalova, I., Hill, A.V., Greenwood, B.M., Peshu ,N., Marsh, K., Kwiatkowski, D.:
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
Nat Genet 22: 145-150
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Bonder, C.S., Finlay-Jones, J.J., Hart, P.H.:
Interleukin-4 regulation of human monocyte and macrophage interleukin-10 and interleukin-12 production. Role of a functional interleukin-2 receptor gamma-chain.
Immunology 96: 529-536
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Musso, T., Calosso, L., Zucca, M., Millesimo, M., Ravarino, D., Giovarelli, M., Malavasi, F., Ponzi, A.N., Paus, R., Bulfone-Paus S.:
Human Monocytes Constitutively Express Membrane-Bound, Biologically Active, and Interferon-gamma-Upregulated
Interleukin-15. Blood 93: 3531-3539
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Abstract PubMed
Bohnenstengel, F.I., Steube, K.G., Meyer, C., Nugroho, B.W., Hung, P.D., Kiet, L.C., Proksch, P.:
Structure activity relationships of antiproliferative rocaglamide derivatives from Aglaia species (Meliaceae)
Z Naturforsch [C] 54: 55-60
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Chen W, Syldath U, Bellmann K, Burkart V, Kolb H:
Human 60-kDa heat-shock protein: a danger signal to the innate immune system
J Immunol 162: 3212-3219
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Sato K, Tomioka H:
In vitro antimicrobial activities of quinolones, rifamycins and macrolides against Mycobacterium tuberculosis and M. avium complex: attempt to establish new assay methods which accurately reflect therapeutic effects of test agents in vivo
Kekkaku 74: 63-70
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Engelmann B, Zieseniss S, Brand K, Page S, Lentschat A, Ulmer AJ, Gerlach E:
Tissue factor expression of human monocytes is suppressed by lysophosphatidylcholine
Arterioscler Thromb Vasc Biol 19: 47-53
1999
Abstract PubMed
Hamik A, Setiadi H, Bu G, McEver RP, Morrissey JH:
Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein
J Biol Chem 274: 4962-4969
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Zughaier SM, Ryley HC, Jackson SK:
A melanin pigment purified from an epidemic strain of Burkholderia cepacia attenuates monocyte respiratory burst activity by scavenging superoxide anion
Infect Immun 67(2): 908-913
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Zughaier SM, Ryley HC, Jackson SK:
Lipopolysaccharide (LPS) from Burkholderia cepacia is more active than LPS from Pseudomonas aeruginosa and Stenotrophomonas maltophilia in stimulating tumor necrosis factor a
Infect Immun 67(3): 1505-1507
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Howie SE, Fernandez ML, Heslop I, Hewson TJ, Cotton GJ, Moore MJ, Innes D, Ramage R, Harrison DJ:
A functional, discontinuous HIV-1 gp120 C3/C4 domain-derived, branched, synthetic peptide that binds to CD4 and inhibits MIP-1alpha chemokine binding
FASEB J 13: 503-511
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Vidal V, Scragg IG, Cutler SJ, Rockett KA, Fekade D, Warrell DA, Wright DJ, Kwiatkowski D:
Variable major lipoprotein is a principal TNF-inducing factor of louse-borne relapsing fever
Nat Med 4: 1416-1420
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Prasad, N.K., Papoff, G., Zeuner, A., Bonnin, E., Kazatchkine, M.D., Ruberti, G., Kaveri, S.V:
Therapeutic preparations of normal polyspecific IgG (IVIg) induce apoptosis in human lymphocytes and monocytes: a novel mechanism of action of IVIg involving the Fas apoptotic pathway
J Immunol; 161:3781-3790
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Finstad, H.S., Myhrstad, M.C., Heimli, H., Lomo, J., Blomhoff, H.K., Kolset, S.O., Drevon, C.A:
Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids
Leukemia, 12:921-929
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Kato, M., Neil, T.K., Clark, G.J., Morris, C.M., Sorg, R.V., Hart, D.N.J:
cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells
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Mahony D, Stringer BW, Dickinson JL, Antalis TM:
DNase I hypersensitive sites in the 5' flanking region of the human plasminogen activator inhibitor type 2 (PAI-2) gene are associated with basal and tumor necrosis factor-alpha-induced transcription in monocytes
Eur J Biochem 256: 550-559
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Gidlof C, Carlson B, Dohlsten M, Totterman TH:
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Eur J Haematol 60: 233-239
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Bergmann S, Siekmeier R, Mix C, Jaross W:
Even moderate cigarette smoking influences the pattern of circulating monocytes and the concentration of sICAM-1
Respir Physiol 114: 269-275
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Strissel PL, Strick R, Rowley JD, Zeleznik-Le NJ:
An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region
Blood 92: 3793-3803
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Sengupta, T.K., Talbot, E.S., Scherle, P.A., Ivashkiv, L.B.:
Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases
Proc. Natl. Acad. Sci. USA 95: 11107-11112
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Melkonyan, H., Hofmann, H.A., Nacken, W., Sorg, C., Klempt, M.:
The gene encoding the myeloid-related protein 14 (MRP14), a calcium-binding protein expressed in granulocytes and monocytes, contains a potent enhancer element in the first intron
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Barrow, E.L.W., Winchester, G.A., Staas, J.K., Quenelle, D.C., Barrow, W.W.:
Use of microsphere technology for targeted delivery of rifampin to Mycobacterium tuberculosis-infected macrophages
Antimicrob. Agents Chemother. 42: 2682-22689
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Abstract PubMed
Lodie, T.A., Reiner, M., Coniglio, S., Viglianti, G., Fenton, M.J.:
Both PU.1 and nuclear factor-kappa B mediate lipopolysaccharide- induced HIV-1 long terminal repeat transcription in macrophages.
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Neumeister, B., Faigle, M., Sommer, M., Zahringer, U., Stelter, F., Menzel, R., Schutt, C., Northoff, H.:
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Infect. Immun. 66: 4151-4157
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Endres, S., Sinha, B., Fülle, H.J.:
Amrinone suppresses the synthesis of tumor necrosis factor-a in human mononuclear cells
Shock, 1: 377-380
1994
Abstract PubMed
McGeehan, G.M., Becherer, J.D., Bast, R.C. jr., Boyer, C.M., Champion, B., Connolly, K.M., Conway, J.G., Furdon, P., Karp, S., Kidao, S., McElroy, A.B., Nichols, J., Pryzwansky, K.M., Schoenen, F., Sekut, L., Truesdale, A., Verghese, M., Warner, J., Ways,:
Regulation of tumor necrosis factor-a processing by a metalloproteinase inhibitor
Nature, 370: 558-561
1994
Abstract PubMed
de Wit, H., Hendriks, D.W., Halie, R.M., Vellenga, E.:
Interleukin-4 receptor regulation in human monocytic cells
Blood, 84: 608-615
1994
Abstract PubMed
Hrboticky, N., Tang, L., Zimmer, B., Lux, I., Weber, P.C.:
Lovastatin increases arachidonic acid levels and stimulates thromboxane synthesis in human liver and monocytic cell lines
J. Clin. Invest., 93: 195-203
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Abstract PubMed
Shattock, R.J., Friedland, J.S., Griffin, G.E.:
Phagocytosis of Mycobacterium tuberculosis modulates human immunodeficiency virus repliaction in human monocytic cells
J. General Virol., 75: 849-856
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Abstract PubMed
Driessen, C., Hirv, K., Rink, L., Kirchner, H.:
Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes
Lymphokine Cytokine Res., 13: 15-20
1994
Abstract PubMed
Zhang, D.-E., Hetherington, C.J., Chen, H.-M., Tenen, D.G.:
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.
Mol. Cell. Biol., 14(1): 373-381
1994
Abstract PubMed
Zhang, D.-E., Hetherington, C.J., Tan, S., Dziennis, S.E., Gonzalez, D.A., Chen, H.-M., Tenen, D.G.:
Sp1 is a critical factor for the monocytic specific expression of human CD14
J. Biol. Chem., 269: 11425-11434
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Abstract PubMed
de Wit, H., Esselink, M.T., Halie, M.R., Vellenga, E.:
Differential regulations of M-CSF and IL-6 gene expression in monocytic cells
Br. J. Haematol., 86: 259-264
1994
Abstract PubMed
Claesson, H.-E., Jakobsson, P.-J., Steinhilber, D., Odlander, B., Samuelsson, B.:
Expression of 5-lipoxygenase and biosynthesis of leukotriene B4 in human monomorphonuclear leukocytes
J. Lipid Mediators, 6: 15-22
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Abstract PubMed
Dickinson, J.L., Antalis, T.M.:
Tissue factor and plasminogen activator inhibitor expression in the differeniation of myeloid leukemic cells
Leukemia, 7: 864-871
1993
Abstract PubMed
Funk, J.O., Kruse, A., Neustock, P., Kirchner, H.:
Helium-neon laser irradiation induces effects on cytokine production at the protein and the mRNA level
Exp. Dermatol., 2: 75-83
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Abstract PubMed
Federsppiel, B., Melhado, I.G., Duncan, A.M.V., Delaney, A., Schappert, K., Clark-Lewis, I., Jirik, F.R.:
Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen
Genomics, 16: 707-712
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Abstract PubMed
Jendrossek, V., Damm, U., Liese, J., Belohradsky, B.H., Gahr, M.:
Is the IFN-gamma-induced enhancement of superoxide production in CGD-phagocytes caused by increased expression of the p47-phox cytosolic protein?
Immunodeficiency, 4: 187-190
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Abstract PubMed
Fan, S.-T., Edgington, T.S.:
Integrin regulation of leukocyte inflammatory functions
J. Immunol., 150: 2972-2980
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Abstract PubMed
Murphy, K.M., Sweet, M.J., Ross, I.L., Hume, D.A.:
Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages
J. Virol., 67: 6956
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Abstract PubMed
Uhm, J.-R., Kettering, J.D., Gridley, D.S.:
Modulation of transforming growth factor-ß1 effects by cytokines
Immunol. Invest., 22: 375-388
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Abstract PubMed
Eisenhut, T., Sinha, B., Gröttrup-Wolfers, E., Semmler, J., Siess, W., Endres, S.:
Prostacyclin analogs suppress the synthesis of tumor necrosis factor-a in LPS-stimulated human peripheral blood mononuclear cells
Immunopharmacol., 26: 259-264
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Abstract PubMed
MacLeod, R.A.F., Voges, M., Drexler, H.G.:
Mono Mac 6: a mature monoblastic leukemia cell line with t(9;11)(p21;q23)
Blood, 82: 3221-3222
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Abstract PubMed
Read, M.A., Cordle, S.R., Veach, R.A., Carlisle, C.D., Hawiger, J.:
Cell-free pool of CD14 mediates activation of transcription factor NF-kB by lipopolysaccharide in human endothelial cells
Proc. Natl. Acad. Sci. USA, 90: 9887-9891
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Abstract PubMed
Labeta, M.O., Durieux, J.-J., Spagnoli, G., Fernandez, N., Wijdenes, J., Herrmann, R.:
CD14 and tolerance to lipopolysaccharide: biochemical and functional analysis
Immunol., 80: 415-423
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Abstract PubMed
Dentener, M.A., von Asmuth, E.J.E., Francot, G.J.M., Marra, M.N., Buurman, W.A.:
Antagonistic effects of lipopolysaccharide binding protein and bactericidal/permeability-increasing protein on lipopolysaccharide-induced cytokine release by mononuclear phagocytes
J. Immunol., 151: 4258-4265
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Abstract PubMed
Guo, M.M.E., Hildreth, J.E.K.:
HIV-induced loss of CD44 expression in monocytic cell lines
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Abstract PubMed
Huang, R., Abrink, M., Gobil, A.E., Nilsson, G., Aveskogh, M., Larsson, L.G., Nilsson, K., Hellman, L.:
Expression of a mast cell tryptase in the human monocytic cell lines U-937 and Mono Mac 6
Scand. J. Immunol., 38: 359-367
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Abstract PubMed
Friedland, J.S., Shattock, R.J., Griffin, G.E.:
Phagocytosis of Mycobacterium tuberculosis or particulate stimuli by human monocytic cells induces equivalent monocyte chemotactic protein-1 gene expression
Cytokine, 5: 150-156
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Abstract PubMed
Neustock, P., Brand, J.M., Kruse, A., Kirchner, H.:
Cytokine production of the human monocytic cell line Mono Mac 6 in comparison to mature monocytes in peripheral blood mononuclear cells
Immunobiol., 188: 293-302
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Abstract PubMed
Labeta, M.O., Durieux, J.-J., Fernandez, N., Herrmann, R., Ferrara, P.:
Release from a human monocyte-like cell line of two different soluble forms of the lipopolysaccharide receptor, CD14
Eur. J. Immunol., 23: 2144-2151
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Abstract PubMed
Wan, C.P., Myung, E., Lau, B.H.S.:
An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes
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Abstract PubMed
Kühn, K., Bertling, W.M., Emmrich, F.:
Cloning of a functional cDNA for human cytidine deaminase (CDD) and its use as a marker of monocyte/macrophage differentiation
Biochem. Biophys. Res. Commun., 190: 1-7
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Abstract PubMed
Uphoff, C.C., Gignac, S.M., Metge, K., Zschunke, F., Radzun, H.J., Drexler, H.G.:
Expression of the monocyte-specific esterase gene in leukemia-lymphoma cell lines
Leukemia, 7: 58-62
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Abstract PubMed
Gessl, A., Willheim, M., Agis, H., Spittler, A., Schedle, A., Krugluger, W., Förster, O., Boltz-Nitulescu, G.:
Tumour necrosis factor augments the expression of Fc IgE receptor (FceRII/CD23) on human monocytic cell lines and down-regulates interleukin-4-driven FceRII expression on monocytes
Immunol., 78: 476-481
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Abstract PubMed
Lin, S.L., Derr, D., Hildreth, J.E.:
A monoclonal antibody against a novel 20-kDa protein induces cell adhesion and cytoskeleton-dependent morphologic changes
J. Immunol., 149: 2549-2559
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Abstract PubMed
Chujor, C.S.N., Kuhn, B., Schwerer, B., Bernheimer, H., Levis, W.R., Bevec, D.:
Specific inhibition of mRNA accumulation for lymphokines in human T cell line Jurkat by mycobacterial lipoarabinomannan antigen
Clin. Exp. Immunol., 87: 398-403
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Abstract PubMed
Schreck, R., Bevec, D., Dukor, P., Baeuerle, P.A., Chedid, L., Bahr, G.M.:
Selection of a muramyl peptide based on its lack of activation of nuclear factor-kB as a potential adjuvant for AIDS vaccines
Clin. Exp. Immunol., 90: 188-193
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Abstract PubMed
Pradines-Figueres, A., Raetz, R.H.:
Processing and secretion of tumor necrosis factor a in endotoxin-treated Mono Mac 6 cells are dependent on phorbol myristate acetate
J. Biol. Chem., 267: 23261-23268
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Abstract PubMed
Geng, J.-G., Heavner, G.A., McEvert, R.P.:
Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions
J. Biol. Chem., 267: 19846-19853
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Abstract PubMed
Friedland, J.S., Remick, D.G., Shattock, R., Griffin, G.E.:
Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines
Eur. J. Immunol., 22: 1373-1378
1992
Abstract PubMed
Endres, S., Fülle, H.-J., Sinha, B., Stoll, D., Dinarello, C.A., Gerzer, R., Weber, P.C.:
Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-a and interleukin-1b by human mononuclear cells
Immunology, 72: 56-60
1991
Abstract PubMed
Willheim, M., Gessl, A., Berger, R., Schedle, A., Luger, T., Föster, O., Boltz Nitulescu, G.:
IL-6 augments Fc IgE receptor (FceRII/CD23) expression on human monoblastic/monocytic cell lines U937, THP-1, and Mono Mac 6, but not on blood monocytes
J. Immunol., 147: 1837-1842
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Abstract PubMed
Taktak, Y.S., Selkirk, S., Bristow, A.F., Carpenter, A., Ball, C., Rafferty, B., Poole, S.:
Assay of pyrogens by interleukin-6 release from monocytic cell lines
J. Pharm. Pharmacol., 43: 578-582
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Abstract PubMed
Stünkel, K.G.E., Hewlett, G., Zeiler, H.J.:
Ciprofloxacin enhances T cell function by modulating interleukin activities
Clin. Exp. Immunol., 86: 525-531
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Abstract PubMed
Nowlin, D.M., Cooper, N.R., Compton, T.:
Expression of a human cytomegalovirus receptor correlates with infectibility of cells
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Abstract PubMed
Rafferty, B., Mower, J.A., Taktak, Y.S., Poole, S.:
Measurement of cytokine production by the monocytic cell line Mono Mac 6 using novel immunoradiometric assays for interleukin-1ß and interleukin-6
J. Immunol. Meth., 144: 69-76
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Abstract PubMed